Project Grant R01CA304272
- Federal Project Grant Award Summary The National Cancer Institute awarded a $712,569 Project Grant to Fred Hutchinson Cancer Center under the Cancer Treatment Research program (CFDA 93.395) effective May 4, 2026 through April 30, 2031. This award supports research investigating the impact of KEAP1/NRF2 (Nuclear Factor Erythroid 2-Related Factor 2) pathway activation on chemotherapy response in small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC). The research addresses a...
- Federal Grant Award Summary The National Cancer Institute awarded Fred Hutchinson Cancer Center a $739,640 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) for the period September 1, 2025, through August 31, 2030. This award supports the development and validation of methods to advance early detection of pancreatic ductal adenocarcinoma (PDAC) by leveraging electronic medical records (EMR) data. The project addresses the critical public health challenge that...
- Federal Grant Award Summary The National Cancer Institute awarded Fred Hutchinson Cancer Center a Project Grant of $737,945 (award date: May 4, 2026; completion date: April 30, 2029) under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop quantitative measurement tools for assessing determinants of evidence-based cancer care interventions. The primary deliverable is the creation of flexible, comparable item banks—collections of survey items that can be tailored to...
- Federal Grant Award Summary Cereus Diagnostics Corp. received a $764,448 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) awarded on August 1, 2025, with completion targeted for July 31, 2028. The company is developing LUNG-FAST (Fragment Analysis, SNP, and Translocations), a rapid polymerase chain reaction (PCR)-based diagnostic test designed to detect clinically actionable lung cancer mutations including EGFR, KRAS, ALK,...
- Federal Grant Award Summary H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. received a $2.99 million Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393), awarded on September 23, 2025, with a completion date of August 31, 2029. This grant funds research to characterize lung cancer screening (LCS) trends and outcomes among people with HIV (PWH) in the United States, addressing a significant gap in empirical...
- Federal Project Grant Award Summary Fred Hutchinson Cancer Center received a $692,368 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) effective June 1, 2026 through May 31, 2031. This award supports research focused on elucidating the MYC (Myc proto-oncogene) transcription factor network and its roles in oncogenic and tumor suppressive pathways. The research will utilize genetically engineered mouse models to investigate how...
- Federal Grant Award Summary The University of Washington received a $686,271 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) effective May 1, 2026 through April 30, 2031. This award supports development of proteomics-driven analysis and robotics-enabled drug testing methodologies applied to microdissected tumors and their microenvironment. The research combines microscale tissue manipulation technologies with...
- Federal Grant Award Summary H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. received a $687,593 Project Grant from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) awarded on May 12, 2026, with a completion date of April 30, 2031. The award funds fundamental research investigating cysteine acquisition and utilization mechanisms in lung adenocarcinoma. The project delivers comprehensive scientific research services focused on...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Washington University a Project Grant totaling $425,088 (Award Date: May 1, 2026; Completion Date: April 30, 2031) under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a comprehensive comparative analysis of lung cancer care and outcomes between Medicare Advantage (MA) and Traditional Medicare (TM) beneficiaries. The research will leverage large national databases to create representative...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Fred Hutchinson Cancer Center a $439,639 Project Grant effective June 1, 2026 through May 31, 2031 under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop comprehensive methodologies and tools for microsimulation model calibration. The project directly addresses critical gaps in cancer screening policy research by creating a flexible, publicly available calibration tool (Aim 1); developing a...
Fred Hutchinson Cancer Center received a $714,192 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) effective June 1, 2026, through May 31, 2031. The award supports the development and validation of a novel lung cancer subtype-specific risk stratification approach designed to address critical limitations in current low-dose computed tomography (CT) screening protocols. The research delivers an integrated diagnostic methodology combining blood autoantibody biomarker detection with quantitative imaging features to differentiate adenocarcinoma, squamous cell carcinoma, and small cell lung cancer risk profiles, enabling earlier diagnosis and improved clinical management of indeterminate pulmonary nodules. The project addresses identified gaps in existing lung cancer screening guidelines by providing subtype-specific risk assessment tools that enhance sensitivity for underdiagnosed cancer types while improving classification accuracy for indeterminate nodules. In concert with established screening protocols, the research products are intended to identify high-risk patients requiring immediate intervention and reduce false-positive diagnostic procedures, thereby advancing the National Cancer Institute's objective to improve early detection strategies and predict disease course in cancer patients.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $714.2k | 6/3/26 |