Project Grant R01CA289668
- This federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) in the amount of $653,819 aims to redefine screening for early detection of pancreatic cancer. The grant will be used by The Johns Hopkins University to: Develop a highly specific blood-based early detection screening test called "PancSeek" for populations at higher risk of pancreatic cancer. Develop risk models that integrate clinical, genomic, molecular, and...
- The Department of Defense's Defense Health Agency awarded a $845,928 Project Grant to The Trustees of Columbia University in the City of New York, Health Sciences Division, to support the "ENHANCING EARLY DETECTION OF PANCREATIC CANCER USING GPT-EMBEDDED EHR MODELS: A NOVEL APPROACH FOR IMPROVED PREDICTIVE PERFORMANCE AND INTERPRETABILITY" research project. This grant, funded through the Military Medical Research and Development program (CFDA 12.420), will focus on developing...
- This Cooperative Agreement award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $690,637 to the Beckman Research Institute of the City of Hope to develop and validate a minimally invasive, highly sensitive, and cost-effective blood-based test for the early detection of pancreatic ductal adenocarcinoma (PDAC). The test will harness the potential of 5-methylcytosine (5MC) and 5-hydroxy methylcytosine (5HMC) DNA modifications on circulating...
- This $471,675 project grant from the Department of Health and Human Services National Institutes of Health National Cancer Institute Cancer Detection and Diagnosis Research program (CFDA 93.394) will fund research at Oregon Health & Science University to develop a nanoparticle-based blood test to distinguish pancreatic cancer from benign pancreatic disease. The researchers will use high conductance dielectrophoresis technology to simultaneously recover different types of cancer-derived...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to the Sloan-Kettering Institute for Cancer Research provides $263,086 to develop a multiparametric endoscopic ultrasound (MPEUS) imaging system and methodology for improved pancreatic cancer screening and characterization. The goal is to create a non-subjective, quantitative approach for detecting and characterizing pancreatic cancer and precursor lesions in high-risk...
- The Cedars-Sinai Medical Center was awarded a $523,670 Project Grant by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to develop an artificial intelligence (AI) model for the early detection of pancreatic tumors using abdominal computed tomography (CT) scans. The key objectives are to: 1) Analyze CT image texture variations in different regions of the pancreas to enhance tumor detection, 2) Integrate distinctive morphological features of the pancreas,...
- This federal Project Grant award of $505,613, provided by the National Cancer Institute (CFDA 93.394 Cancer Detection and Diagnosis Research), will support the development of statistical and computational approaches to harness genomic data and translate findings into precision prevention strategies for cancer. The key objectives are to: Develop deep learning-based methods to identify tumor subtypes linked to adverse outcomes and robust data integration approaches to assess associations between...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $402,401.00 to Emory University to develop a PET CCR2 imaging agent to profile the tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC). The project aims to advance diagnostic and profiling capabilities for this highly aggressive cancer, which is the 4th leading cause of cancer-related death. The award has a period of performance from July 4, 2024 to...
- This federal Project Grant award of $218,055.00, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research to enhance early detection of pancreatic cancer using GPT-embedded electronic health record (EHR) models. The award, which runs from August 1, 2025 to July 31, 2028, is provided to The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division. This research aims to...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $191,700.00 to Cedars-Sinai Medical Center to conduct research on the etiology and tumor characteristics of early-onset pancreatic cancer. The research aims to identify modifiable risk factors associated with the development of early-onset pancreatic cancer and characterize the clinicopathological and molecular features of tumors in affected patients. The award period runs from...
This federal Project Grant awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $739,640 to the Fred Hutchinson Cancer Center to develop methods for advancing the early detection of pancreatic ductal adenocarcinoma (PDAC) by leveraging electronic medical records (EMR) data. The key objectives of the project are to: This 5-year project, starting September 2025, aims to advance the scientific understanding and clinical implementation of PDAC early detection methods using EMR data. The findings could lead to earlier diagnostic testing or interventions and enable faster identification of cancer trends or risk factors to support quicker clinical action.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1k | 9/18/25 | ||
| Not listed | $737.5k | 8/25/25 |