Project Grant R01CA310932
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Fred Hutchinson Cancer Center a $439,639 Project Grant effective June 1, 2026, through May 31, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). This award supports research focused on developing methodologies for microsimulation model calibration—a critical technical process for ensuring that computational models used in cancer screening and prevention policy align with real-world...
- Federal Grant Award Summary Fred Hutchinson Cancer Center received a $712,569 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) awarded on May 4, 2026, with a completion date of April 30, 2031. The research project investigates the KEAP1/NFE2L2 (NRF2) pathway's role in chemoresistance in small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC). The deliverables include the development and validation of NRF2 inhibitor...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Fred Hutchinson Cancer Center a Project Grant totaling $139,184 under the Cancer Research Manpower program (CFDA 93.398) for the period of July 1, 2025, through June 30, 2027. This award funds research investigating the role of RNA components of the translation apparatus in prostate cancer plasticity and therapy response. The project focuses on elucidating how prostate cancer leverages transfer RNA (tRNA) and 5'...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc., a Project Grant of $734,942 under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. This project addresses cardiovascular disease (CVD) risk in breast cancer survivors by generating novel DNA methylation biomarker data from the Pathways Study, a prospective cohort of 4,504 women diagnosed with...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Pittsburgh a $649,620 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) effective May 1, 2026, through April 30, 2031. This research project examines the impacts of Medicare Advantage insurance coverage on cancer care access, quality, and outcomes for older adults with the four most prevalent cancers: breast, colorectal, lung, and prostate. The research addresses a...
- Federal Project Grant Award Summary Fred Hutchinson Cancer Center received a $129,708 Project Grant award from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2025 through July 31, 2026. The award supports the development of computational tools and methodologies for analyzing single-cell molecular data to advance understanding of cellular differentiation and cancer progression. Specifically, the...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Fred Hutchinson Cancer Center a $140,854 Project Grant under the Cancer Research Manpower program (CFDA 93.398) effective July 1, 2025, through December 31, 2026. This K99/R00 Pathway to Independence Award supports research training and career development for Dr. Karl Cristie Figuracion, PhD, ARNP, a postdoctoral research fellow transitioning to an independent scientist. The award funds a structured training and mentorship...
- Federal Grant Award Summary The National Cancer Institute awarded The Johns Hopkins University a Project Grant of $130,301 under the Cancer Cause and Prevention Research program (CFDA 93.393), with an award date of September 5, 2025, and a project completion date of August 31, 2030. This award supports extensions to the Surveillance, Epidemiology, and End Results (SEER)-Medicare Database, a critical data linkage that connects Medicare claims with cancer registry enrollment data. The primary...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Fred Hutchinson Cancer Center $169,776 under the Cancer Research Manpower program (CFDA 93.398) for a two-year project (August 1, 2025–July 31, 2027) titled "Unraveling Myeloid-Mediated Mechanisms of Immunotherapy Resistance in Prostate Cancer Bone Metastases at Single-Cell Resolution." This project grant funds biomedical research training and investigator-initiated research focused on identifying and...
- Federal Grant Award Summary The National Cancer Institute awarded $125,619 to the Stowers Institute for Medical Research under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. This Project Grant supports research into centromere biology and chromosome segregation mechanisms that contribute to genomic instability—a hallmark of cancer development. The primary deliverables include experimental research characterizing how natural...
Fred Hutchinson Cancer Center received $737,945 in project grant funding from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) for the period of May 4, 2026, through April 30, 2029. The project, titled "Measuring Provider and Intervention Characteristic Determinants of Evidence-Based Cancer Care," will develop flexible, quantitative measurement tools using Item Response Theory (IRT) to assess factors that facilitate or prevent the implementation of evidence-based interventions (EBIs) in cancer care settings. The deliverables will consist of item banks—tailored collections of survey items that measure intervention and provider characteristic determinants across diverse cancer care settings and populations, including community oncology, academic centers, treatment, survivorship, and end-of-life care contexts. These measures will address critical gaps in implementation science by providing comparable, valid quantitative tools that can track determinants over time and inform implementation decisions. The project addresses the current challenges of inconsistent assessment tools, limited validity and reliability in existing measures, and the difficulty of translating continuous quantitative scores into dichotomous yes/no implementation decisions, thereby supporting the broader NCI objective of moving evidence-based cancer care practices into routine clinical use to reduce overall cancer burden.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $737.9k | 5/5/26 |