Project Grant R01CA303699
- The National Cancer Institute (NCI) awarded a $637,596 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to test a video-based intervention designed to reduce defensive colorectal cancer information avoidance and increase colorectal cancer screening rates. The 5-year project will conduct a randomized controlled trial to confirm the intervention's mechanisms of increasing self-efficacy and positive affect, and evaluate its efficacy in reaching those who tend to...
- This Project Grant award, provided by the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393), will fund a study to evaluate the impact of social determinants of health (SDOH) on early-onset colorectal cancer (EOCRC) diagnosis, treatment delays, and survival, with a focus on underserved populations in Kentucky and Georgia. The $192,610 award will support a 2-year epidemiologic study that aims to elucidate the relationship between SDOH measures and...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $456,764 to the University of Chicago to study differences in bile acid metabolism and responses between African Americans and non-Hispanic whites. The goal is to determine if these differences could contribute to the higher colorectal cancer incidence and mortality rates observed in the African American population. Specifically, the research will: 1) compare serum...
- The National Cancer Institute (NCI) awarded a $432,304 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to The Trustees of Columbia University in the City of New York, Health Sciences Division. The grant, awarded on January 3, 2025, supports a 5-year research project focused on "Enhanced Cancer Risk Predictions in Underrepresented Populations through Robust Multi-Source Data Integration." The project aims to develop novel data integration methods to...
- This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $415,257 to the University of Virginia to conduct research aimed at identifying epigenetic and transcriptomic drivers of racial disparities in colorectal cancer risk and site-specific tumor development. The key products and services to be delivered under this 2-year award include: Identifying site-specific DNA methylation-associated gene expression signatures across different...
- This $192,888 Project Grant award from the National Cancer Institute's Cancer Research Manpower program (CFDA 93.398) supports a research project at the University of Virginia (UVA) to investigate the use of normal colon organoids for identifying causal genetic variants associated with colorectal cancer risk. The key objectives of the project are to: 1) test the hypothesis that colorectal cancer GWAS genes are cell type-specific, and 2) determine the role of these genes within colon epithelial...
- This $5,041,790 cooperative agreement award from the National Cancer Institute (NCI), under the Cancer Centers Support Grants program (CFDA 93.397), will fund research projects at the University of California, San Francisco (UCSF) to improve cancer health disparities. The key products and services to be delivered include: Three translational cancer health disparities research projects focused on meningioma, prostate cancer, and breast cancer. The projects aim to evaluate the interplay of...
- The National Cancer Institute (NCI) awarded a $107,071 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) to Rockefeller University, effective March 1, 2025 through February 28, 2029. The grant supports research to investigate the role of inter-organellar communication, specifically between the endoplasmic reticulum and mitochondria, in metabolic reprogramming and cellular plasticity in colorectal cancer. Key objectives include identifying the molecular mechanisms...
- The National Cancer Institute (NCI), a division of the Department of Health and Human Services, awarded Drexel University a $588,359 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393). The grant, which runs from May 19, 2025 to April 30, 2030, will evaluate the efficacy of a multi-level intervention, referred to as "EATWELL", designed to promote adherence to the dietary guidelines for cancer prevention recommended by the World Cancer Research Fund and...
- The National Cancer Institute (NCI) awarded a $621,570 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to Arizona State University (ASU) on August 8, 2025. The grant supports research to determine the impact of maternal obesity on the transformative risk of colorectal cancer (CRC) in offspring by directly assessing the developmental programming of intestinal stem cells during pre- and postnatal growth. The research aims to investigate how naive exposure to an...
The U.S. National Cancer Institute awarded a $724,840 Project Grant to the Regents of the University of California, San Francisco under the Cancer Cause and Prevention Research (CFDA 93.393) federal grant program. The grant supports a 5-year research project to investigate how persistent poverty impacts the risk of colorectal cancer through place-based factors, health behaviors, and underlying biological mechanisms. The study will leverage data from two large, geographically diverse U.S. cohorts to assess the associations between residing in persistent or intermittent poverty areas, the social and built environment, health behaviors, and colorectal cancer incidence. This multidisciplinary research aims to elucidate the multilevel drivers of colorectal cancer disparities and inform targeted prevention strategies for high-risk populations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $724.8k | 8/21/25 |