Project Grant R01AG099722
Award Date 9/1/26
Completion Date 5/31/31
Dollars Obligated $746K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, NY 10029, USA
Similar Awards
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $704,145 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and apply computational methods for inferring the natural history of Alzheimer's disease from sparse longitudinal molecular and neuroimaging data. The recipient will develop an innovative approach that leverages temporal signal in sparse longitudinal datasets to reconstruct the timeline of Alzheimer's disease progression and...
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $1,393,471 on September 19, 2025, under the Aging Research program (CFDA 93.866) to investigate clonal hematopoiesis, epigenetic changes, social determinants of health, and behavioral risk factors as predictors of accelerated aging in people with HIV, with performance through June 30, 2030, in New York, NY. The research examines why people with HIV experience multimorbidities, functional decline, and cognitive...
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $230,388 on March 4, 2026, under the Aging Research program (CFDA 93.866) to dissect the role of the PICALM/EED locus on myeloid cells in Alzheimer's disease. The recipient will conduct research to understand how an Alzheimer's disease risk enhancer on chromosome 11 influences expression of two target genes—PICALM (phosphatidylinositol binding clathrin assembly protein) and EED (embryonic ectoderm development)—and to...
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $2.944 million on June 1, 2026, under the Aging Research program (CFDA 93.866) to investigate systemic roles of apolipoprotein E (APOE) genotypes in central nervous system health and Alzheimer's disease pathology. The research uses plasma transfer and parabiosis models to examine how blood-borne factors and APOE genotype-specific mediators influence blood-central nervous system neuroimmune communication. The...
- The National Institute on Aging awarded New York University $712,578 on February 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a prospective study identifying viral infections associated with cognition decline and Alzheimer's disease risk across three prospective cohorts. The award supports comprehensive serologic profiling using VirScan, a bacteriophage immunoprecipitation sequencing technology, to detect immune responses to human viruses and analyze antiviral antibodies in...
- The National Institute on Aging awarded The Trustees of Columbia University in the City of New York $705,594 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate how pathogen exposure history and chronic latent infections influence Alzheimer's disease and related dementias risk across two distinct human populations. The project examines infection burden and its relationship to Alzheimer's disease biomarkers and cognitive decline by integrating existing longitudinal...
- The National Institute on Aging awarded The Research Foundation For The State University Of New York (operating as Stony Brook University) $454,937 on February 15, 2026, under the Aging Research program (CFDA 93.866) to investigate the regulatory landscape of neurodegeneration using single-cell spatial multiomics approaches. The research integrates chromatin accessibility and protein-level measurements to characterize how cells near Alzheimer's disease hallmarks—amyloid-beta and tau—regulate...
- The National Institute of Neurological Disorders and Stroke awarded Icahn School of Medicine at Mount Sinai $1,967,309 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to dissect the role of small non-coding RNAs in microglia-driven neuroinflammation in Alzheimer's disease. The funded research will elucidate how small non-coding RNAs—including microRNA isoforms, transfer RNA-derived fragments, ribosomal RNA-derived...
- The National Institute on Aging awarded $133,110 to Icahn School of Medicine at Mount Sinai on September 5, 2026, under the Aging Research program (CFDA 93.866) for project K99AG097980. The recipient will integrate single-nucleus and spatial transcriptomics with machine-learning models to establish a comprehensive lifespan reference of the healthy human prefrontal cortex and identify Alzheimer's disease-specific deviations. During the K99 mentored phase, the work will harmonize single-nucleus...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $422,125 to the Board of Regents of the University of Nebraska on June 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the roles of misfolded protein aggregates on latent HIV reservoirs in simian immunodeficiency virus–infected, antiretroviral therapy–treated aged rhesus macaques. The research examines how age-associated amyloid fibril deposition affects the reactivation and...