Project Grant R01AG097793
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of Wisconsin–Madison a Project Grant totaling $698,690 under the Aging Research program (CFDA 93.866) to investigate the molecular mechanisms underlying age-related skeletal muscle dysfunction. The five-year research initiative, commencing February 1, 2026 and concluding January 31, 2031, will deliver scientific research products focused on understanding how aging differentially affects slow versus fast...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Alabama at Birmingham $2,663,195 on September 15, 2025, under the Aging Research program (CFDA 93.866) to conduct a four-year research project examining amyloid-mediated cognitive dysfunction in bacterial pneumonia following traumatic brain injury (TBI). The research will investigate the mechanisms by which Pseudomonas aeruginosa pneumonia exacerbates cognitive decline in TBI patients through...
- Federal Project Grant Award Summary The University of Washington received a $485,676 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective August 15, 2025, through April 30, 2030, to conduct research quantifying neuromuscular changes in the aging larynx. The project addresses age-related vocal atrophy (ARVA), a condition affecting voice, swallowing, and communication across a substantial portion of the population, with associated impacts on social...
- Federal Project Grant Award Summary The National Institute on Aging (NIA), through its Aging Research program (CFDA 93.866), awarded $634,658 to the University of Colorado-Denver on February 15, 2026, with a project completion date of November 30, 2030. This Project Grant supports biomedical research investigating the interaction between systemic endothelial glycocalyx fragility and brain dysfunction in aged sepsis survivors. The research addresses a critical public health challenge, as sepsis...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $293,454 to the University of Wisconsin–Milwaukee, with an award date of January 15, 2026, and completion date of December 31, 2030, under the Aging Research program (CFDA 93.866). The research project investigates the neural mechanisms underlying memory generalization and integration in older adults through three fMRI-based experiments. The primary deliverables include behavioral and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Massachusetts Medical School $460,625 on May 15, 2025, under the Aging Research program (CFDA 93.866) to conduct a two-year research project concluding April 30, 2027. This project grant supports biomedical research investigating the role of Mixed Lineage Kinase Domain Like Pseudokinase (MLKL) in platelet-mediated immune responses during respiratory viral infections in older adults. The research...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded $198,164 through its Aging Research program (CFDA 93.866) to the University of Pennsylvania for an Individual National Research Service Award (NRSA) project commencing October 29, 2025, with completion targeted for May 31, 2027. This research training award funds a qualitative descriptive study examining dementia-friendly hospitalization practices with a focus on family caregiver inclusion. The project will deliver...
- Federal Grant Award Summary The National Institute on Aging (NIA), under its Aging Research program (CFDA 93.866), awarded a $3.28 million Project Grant to Harvard T.H. Chan School of Public Health on September 15, 2025, with completion targeted for August 31, 2029. This research initiative addresses the interplay between herpesvirus infection, immune responses, apolipoprotein E (APOE) genotype, and tau-pathology development in Alzheimer's disease (AD). The primary deliverable is scientific...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Regents of the University of California, San Francisco $460,283 through the Aging Research program (CFDA 93.866) to conduct a two-year research project from September 1, 2025 through August 31, 2027. This Project Grant supports biomedical research directed toward understanding the aging process and age-related diseases, with the funded research examining the role of reverse electron transport (RET) inhibition in...
- Federal Project Grant Award Summary The National Institute on Aging awarded $1,381,726 to the University of California, San Francisco on August 1, 2025, under the Aging Research program (CFDA 93.866) to conduct a five-year research project examining the mechanisms of microbiome-joint crosstalk in osteoarthritis (OA) pathogenesis. The research will investigate how the gut microbiome influences age-related joint degeneration and systemic inflammation, with the hypothesis that gut microbiota...
The National Institute on Aging (NIA) awarded $646,358 to the University of Wisconsin-Madison on June 15, 2026, under the Aging Research program (CFDA 93.866) to support a five-year observational research study examining the interplay between oral hypofunction, dysphagia (swallowing dysfunction), and the airway microbiome in pneumonia pathogenesis among older adults. The research project, scheduled for completion on February 28, 2031, will deliver comprehensive scientific knowledge addressing a critical patient safety gap by characterizing profiles of oral and swallowing dysfunction in elderly emergency department patients presenting with pneumonia of various bacterial etiologies. Pneumonia represents the leading infectious cause of morbidity and mortality in older Americans, with incidence increasing exponentially with age, yet the relationship between oral dysfunction, swallowing impairment, and pneumonia risk has not been well characterized. The award supports an observational study incorporating objective diagnostic evaluations of both oral and swallowing function combined with metagenomic analyses and microphysiological modeling to assess aspiration mechanisms. The research will generate evidence to inform clinical practice, improve diagnostic classification of pneumonias, support targeted antibiotic therapy decisions, and identify appropriate candidates for swallowing and oral rehabilitation interventions. By addressing this knowledge gap through rigorous scientific investigation at a leading research institution, the project contributes to the NIA's mission of supporting biomedical research directed toward understanding age-related diseases and the special health needs of aging populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $646.4k | 6/9/26 |