Project Grant R01AG096179
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $302,960 to Harvard T.H. Chan School of Public Health to conduct research on identifying individuals who would benefit most from intensive blood pressure control for preventing cognitive decline and dementia, as well as those at risk of serious adverse events. The research will utilize advanced statistical methods and pooled data from multiple large-scale randomized trials to detect...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), provides $2,612,229 to the University of Delaware to conduct research on the benefits and harms of different hypertension management strategies for nursing home residents with Alzheimer's disease and related dementias (ADRD). The 4-year project, running from Sep 1, 2025 to Aug 31, 2029, aims to: 1) describe current hypertension treatment approaches in this...
- This Project Grant award, valued at $2,380,018.00, was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to the Regents of the University of Michigan. The overarching goal is to investigate the influence of cumulative hyperglycemia, type 2 diabetes management, and vascular risk factors on cognitive decline and Alzheimer's disease and related dementias (ADRD) risk. The research team will leverage pooled cohort studies and individual participant data meta-analysis to...
- This federal Project Grant award for $152,957 was provided by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The award titled "Genetic Predisposition to Elevated Blood Pressure and Midlife Cognitive Function: Exploring the Impact of Lifespan Risk Factors and Polygenic Risk Scores" aims to investigate the relationship between genetic predisposition to hypertension and midlife cognitive function and Alzheimer's disease and related...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) is for the research project "Impact of Hypertension and Aging on Postoperative Delirium". The $715,801 grant, awarded on June 1, 2025, supports Duke University's research to elucidate the contributions of endothelial cells and perivascular macrophages to surgery-induced neuroinflammation, blood-brain barrier disruption, and delirium-like behavior in aging and hypertension. The overarching...
- This federal Project Grant award for $2,557,260 from the National Institute on Aging (CFDA 93.866 Aging Research program) will fund a study titled "Lifecourse Predictors and Mechanisms of Early Clinical ADRD among Black and White Adults in their Sixties". The study aims to investigate the transition from midlife to early late-life and identify the earliest manifestations of Alzheimer's disease (AD) and Alzheimer's disease-related disorders (ADRD) in a diverse population. The research...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a $163,080 research project titled "Bridging Gaps to Translate Plasma Alzheimer's Disease Biomarkers to Diverse Populations." The project, led by the University of Texas Health Science Center at San Antonio, aims to address critical gaps in understanding the performance of plasma biomarkers for Alzheimer's disease and related dementias in diverse population cohorts, including in the...
- This federal Project Grant award of $441,612 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Trustees of Boston University (Boston University Medical Campus) supports research to evaluate the use of digital cognitive measures, such as digital pen tasks and voice recordings, to monitor early cognitive decline in relation to modifiable Alzheimer's disease risk factors. The project aims to leverage the Framingham Heart Study's longitudinal data on digital cognitive...
- This $4,444,978 federal Project Grant award, issued by the National Institute on Aging (CFDA 93.866 Aging Research program), supports research to characterize cognitive reserve and identify modifiable factors that promote cognitive reserve and resilience to Alzheimer's disease and related dementias (ADRD) among older adults in India, with a focus on those who lack formal education. The project aims to: 1) compare brain pathology measures and their contributions to cognition between older...
- The National Institute on Aging (NIA) has awarded a $640,906 project grant under CFDA 93.866 Aging Research to the University of Wisconsin-Madison to conduct research on "Elucidating Cerebrovascular Disease Pathways to Cognitive Decline with Vascular Neuroimaging." The 5-year project aims to utilize advanced neuroimaging techniques to understand the vascular contributions to cognitive impairment and dementia (VCID), and assess their relationship to Alzheimer's disease proteinopathy....
This $5,789,766 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will examine the effects of intensive blood pressure control on mild cognitive impairment, dementia, and plasma biomarker trajectories by Alzheimer's disease pathology. The study aims to elucidate neuroprotective effects in the racially and ethnically diverse SPRINT trial cohort. The University of Utah is the primary awardee and will conduct this research over a period of approximately 5 years, from September 2025 through June 2030. The project seeks to advance scientific understanding of the relationship between hypertension, cognitive impairment, and dementia, particularly among underrepresented minority populations who face disproportionately higher rates of these conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $5.8m | 9/15/25 |