This $2,497,615 federal Project Grant award, funded by the National Institute on Aging under the Aging Research program (CFDA 93.866), aims to evaluate the impact of new Medicare home health agency (HHA) payment policies on healthcare utilization and outcomes for Medicare beneficiaries with Alzheimer's disease and related dementias (ADRD).
The project has three key objectives: 1) characterizing changes in the ADRD beneficiary population eligible for HHA services, 2) evaluating the effect of...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,380,018 to the Regents of the University of Michigan to conduct research on the impact of type 2 diabetes and prediabetes on cognitive decline and Alzheimer's disease risk over the life course. The research team will quantify how cumulative hyperglycemia and diabetes management affect cognitive trajectories and Alzheimer's disease risk, and identify potential mechanisms linking...
This $1,276,687 Project Grant, awarded by the National Institute on Aging (CFDA 93.866 Aging Research), aims to improve understanding of the factors driving clonal hematopoiesis (CH) evolution and its association with age-related diseases like cardiovascular disease and Alzheimer's disease.
The grant supports a collaborative research effort led by Washington University, with a sub-award to Harvard T.H. Chan School of Public Health. Key activities include leveraging data from large biobanks...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,399,431 to Boston University Medical Campus to develop a digital cognitive health resource for the early detection and prevention of Alzheimer's disease and related dementias. The project will leverage the Boston University Alzheimer's Disease Research Center cohort to collect longitudinal digital cognitive phenotypes using technologies like digital recorders, pens, and smartphone...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,673,338 in funding to The Regents of the University of California, San Francisco to conduct research on the association between hypertension, blood pressure targets, and Alzheimer's disease and dementia risk among U.S. veterans.
The key objectives of this 5-year study are to: 1) estimate the association between hypertension and Alzheimer's disease/dementia risk among U.S. veterans,...
This $831,583 Project Grant award from the National Institute on Aging's (CFDA 93.866) Aging Research program will support a study on the physiological mechanisms underlying microvascular impairment in adults with elevated genetic risk for Alzheimer's disease. The five-year project, led by The General Hospital Corporation (doing business as Massachusetts General Hospital), aims to elucidate how the APOE-E4 genetic risk factor contributes to reductions in cerebral blood flow and oxygen...
This Project Grant award, provided by the National Institute on Aging (CFDA 93.866 - Aging Research), will support a comprehensive research project to investigate the neurobiological mechanisms underlying daily life activity participation in older adults and its relationship to Alzheimer's disease pathology. The $148,568 award, with a performance period from November 2024 to January 2026, will allow Brandeis University to employ a multilevel, multimodal approach combining ecological momentary...
This federal Project Grant award, provided by the National Institute on Aging (CFDA 93.866 Aging Research), will fund a research study titled "The Effects of Changing Health Care Markets on Cardiovascular and Cerebrovascular Care and Outcomes". The total award amount is $774,972 with a project period from September 15, 2024 to August 31, 2029.
The study aims to quantify the effects of changes in the healthcare market, such as hospital mergers/acquisitions and openings/closures, on...
This $5,262,301 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Trustees of Boston University, doing business as Boston University Medical Campus, aims to improve causal inference in Alzheimer's disease prevention research on modifiable risk factors. The overall TIME-AD project will use an evidence triangulation framework to strengthen causal inference in observational data, evaluating the effects of alcohol use, depression, vision/hearing...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $460,625 to the University of Massachusetts Medical School to dissect the role of cellular senescence pathways in the pathogenesis of Alzheimer's disease (AD). The project aims to use human induced pluripotent stem cell (iPSC)-based AD models to independently investigate the impact of the p53/p21 and p16 senescence pathways on AD-related cellular pathologies in differentiated cortical...