Project Grant R01AG092807
- Federal Project Grant Summary Augusta University Research Institute, Inc. (AURI) received a $542,699 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded January 1, 2026, with a completion date of December 31, 2030. The grant supports biomedical research investigating epigenetic mechanisms underlying the selective vulnerability of parvalbumin (PV)-positive neurons in the entorhinal cortex during aging and Alzheimer's disease (AD). The...
- Federal Grant Award Summary The National Institute on Aging awarded The Salk Institute for Biological Studies a Project Grant totaling $785,348 under the Aging Research program (CFDA 93.866) to investigate the mechanisms linking chronic sleep disruption (CSD) to accelerated aging and reduced healthspan. The research, conducted at the Institute's La Jolla, California facility from August 15, 2025 through July 31, 2027, will generate scientific knowledge regarding whether long-term sleep...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Regents of the University of California, San Francisco $3.3 million through the Aging Research program (CFDA 93.866) on September 15, 2025, for a four-year project period concluding September 14, 2029. This renewal grant (R01AG059677) funds a 40-year longitudinal follow-up study of the National Heart, Lung, and Blood Institute Growth and Health Study (NGHS) cohort, examining the relationship between early life...
- Federal Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded the University of Virginia a Project Grant of $1,044,334 effective August 1, 2025, through May 31, 2030. This research award supports investigation into the mechanisms of ribosomal DNA (rDNA) instability during aging, with the goal of understanding how genomic instability—a hallmark of aging conserved across species—contributes to cellular aging processes. The project will...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $690,865 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) on January 15, 2026, under the Aging Research program (CFDA 93.866). The award supports research through December 31, 2030, investigating the mitochondrial and energetic underpinnings of resilience in human aging. The research leverages two unique human datasets—the MISBIE study (which includes patients with...
- Federal Grant Award Summary The Buck Institute for Research on Aging received a $809,486 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 1, 2026, with completion scheduled for January 31, 2031. This award supports biomedical research investigating the role of oxidation resistance 1 (OXR1) and retromer proteins in brain aging and Alzheimer's Disease and Related Dementias (ADRD). The research deliverables include...
- Federal Project Grant Award Summary Weill Medical College of Cornell University received a $109,076 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded March 3, 2026, with completion scheduled for September 2, 2029. The award supports research investigating vulnerable cell populations in aging-induced circadian clock remodeling and disruption through advanced genomic analysis techniques. The research deliverables center on high-throughput...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Columbia University's Health Sciences Division a Project Grant of $852,273 under the Aging Research program (CFDA 93.866), effective September 1, 2025, with completion targeted for May 31, 2030. This project delivers comprehensive research services focused on genetic mapping of N6-methyladenosine (M6A) and pseudouridine (Ps) RNA modifications in the aging human brain and their relationship to Alzheimer's disease...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Ohio State University $1,391,989 on September 1, 2025, under the Aging Research program (CFDA 93.866) to establish the NCHAT Stress Biology Study (NCHAT-BIO). This project grant, with completion targeted for April 30, 2030, adds comprehensive biological data collection to the existing National Couples' Health and Time Study, a longitudinal, population-representative study of 3,642 coupled adults ages 22-67 with...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Washington University a Project Grant valued at $256,746.00 under the Aging Research program (CFDA 93.866) on August 15, 2025, with completion targeted for May 31, 2030. The award supports research comparing epigenetic, proteomic, and magnetic resonance imaging (MRI) aging clocks in sporadic and autosomal-dominant Alzheimer disease (AD). The research will utilize machine learning-based clock models to estimate...
Augusta University Research Institute, Inc. (AURI) received a $646,620 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective June 1, 2026, through April 30, 2031. The award supports longitudinal research examining the mechanisms through which early-life psychosocial stress contributes to accelerated biological aging in midlife. The project leverages two well-established longitudinal cohorts tracking over 1,000 participants from childhood into midlife to investigate how chronodisruptive behaviors—including irregular sleep patterns, late meal timing, and disrupted rest-activity rhythms—and circadian dysfunction serve as key pathways linking early-life stress to aging-related outcomes such as cardiovascular disease and cognitive decline. The research deliverables include comprehensive analysis of chrono-behaviors and circadian biomarkers as mechanisms of accelerated aging, utilizing repeated measures of behavioral and biological data across the study population's lifespan. By examining the interconnection between the stress-response system and the circadian timing system, this project will generate scientific knowledge addressing a significant gap in longitudinal aging research and inform prevention or intervention strategies to extend healthy lifespan by slowing the aging process itself—aligning with the NIA's mission to support biomedical and behavioral research on aging and age-related diseases.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $646.6k | 5/26/26 |