Project Grant R01AG091718

Award Date 4/15/25
Completion Date 3/31/30
Dollars Obligated $1.7M
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
San Francisco, CA 94143, USA
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This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $132,116 in funding to The Regents of the University of California, San Francisco (UCSF) to conduct research evaluating social and clinical risk factors that influence the progression from mild cognitive impairment (MCI) to Alzheimer's disease and related dementias (AD/ADRD). The key objectives are to: 1) Develop a natural language processing algorithm to identify MCI cases from UCSF's...
The National Institute on Aging (NIA) awarded a $7,249,563 Project Grant under the Aging Research federal grant program (CFDA 93.866) to the Regents of the University of California, San Francisco (UCSF). This 3-year award, starting on Aug 1, 2023, will support research to characterize the structural properties and variability of tau protein aggregation in different brain cell types and at different disease stages of Alzheimer's and related dementias (ADRD). The project aims to develop new...
This $1,277,367 Project Grant was awarded by the National Institute on Aging (NIA) under CFDA Program 93.866 - Aging Research. The grant funds a 5-year study to investigate the transition from midlife to early late-life (ages 60-65) and the development of early clinical Alzheimer's disease and related dementias (ADRD) among Black and White adults. The study aims to identify life course predictors and underlying mechanistic pathways, including the influence of cardiovascular disease risk...
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This $4,276,054 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support mathematical modeling and analysis to investigate the selective vulnerability of specific brain regions, cell types, and neural networks in mouse models of tauopathy, a key pathological process in Alzheimer's disease. The project aims to quantitatively test and validate hypotheses regarding selective vulnerability driven by protein aggregation, clearance, and...
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This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $800,700 in funding to The Regents of the University of California, San Francisco (UCSF) to conduct a longitudinal, multimodal imaging study. The goal is to elucidate the role of neuronal dysfunction and hyperexcitability in the early biological progression of Alzheimer's disease. The study will identify the earliest manifestations of neural circuit hyperexcitability that predict the...
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This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,215,724 to the University of California, San Diego (UCSD) for a project titled "INTRINSIC CSF OUTFLOW METRICS FOR MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE." The award aims to develop a novel, non-invasive MRI technique to study intrinsic cerebrospinal fluid (CSF) outflow metrics in healthy older adults, individuals with mild cognitive impairment (MCI), and those...
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