Project Grant R01AG091450
- Federal Project Grant Award Summary Harvard T.H. Chan School of Public Health received a $3.28 million Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 15, 2025, through August 31, 2029. The award funds a longitudinal epidemiological research study investigating the relationship between herpesvirus infection, immune responses, apolipoprotein E (APOE) genotype, and tau-pathology development in Alzheimer's disease...
- Federal Grant Award Summary New York University School of Medicine received a $642,063 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective January 15, 2026, with completion targeted for December 31, 2030. The award supports a collaborative research investigation examining gabaergic microcircuits in the hippocampal CA1 region to identify cellular targets and neuromodulatory mechanisms for early-stage Alzheimer's disease (AD)...
- Federal Project Grant Award Summary Award Details: New York University School of Medicine received a $724,813 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective January 1, 2026, through November 30, 2030. The award supports prospective research investigating the relationship between midlife circulating autoantibodies (AAbs) and Alzheimer's disease (AD) risk in women. Research Objectives and Products: This project addresses a critical gap...
- Federal Grant Award Summary New York University was awarded $1,049,816 through the National Institute on Aging's Aging Research program (CFDA 93.866) effective May 15, 2025, with a completion date of January 31, 2029. This project grant supports the development of statistical methodologies to improve the estimation and prediction of Alzheimer's disease (AD) progression using longitudinal cohort study data. The research addresses critical gaps in current analytical approaches by developing...
- Federal Project Grant Award Summary Baylor College of Medicine received a $3,039,032 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective August 15, 2025, through July 31, 2029. The research initiative investigates the relationship between SARS-CoV-2 (COVID-19) infection and the initiation and acceleration of Alzheimer's disease (AD) and related dementias (AD/RD), including Pick's disease, frontotemporal dementia, and other...
- Federal Grant Award Summary New York University received a $1,012,879 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 5, 2025, with completion anticipated by August 31, 2029. The award supports the development of three novel statistical machine learning methods designed to enhance the understanding, diagnosis, and prediction of Alzheimer's disease using multi-view data integration. The primary deliverables include: (1) a...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Trustees of Columbia University in the City of New York a $2,957,210 Project Grant under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This award funds comprehensive biomedical research investigating the role of CD44 astrocytes in Alzheimer's disease (AD) pathophysiology. The research project will elucidate the functional mechanisms by which CD44 upregulation...
- Federal Project Grant Award Summary New York University School of Medicine received a $130,302 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective July 15, 2025, with an ultimate completion date of March 31, 2030. This research award supports a multi-aim investigation into the selective vulnerability of basal forebrain cholinergic neurons (BFCNs) to tau pathology in Alzheimer's disease. The project will deliver scientific...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $509,413 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 15, 2025 through May 31, 2030. This award funds scientific research investigating epitranscriptomic regulation of microglia in Alzheimer's disease (AD), with the primary deliverable being novel research findings and analysis concerning how adenosine methylation...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Icahn School of Medicine at Mount Sinai a Project Grant totaling $839,933 under the Aging Research program (CFDA 93.866), effective September 1, 2025, through May 31, 2030. This award supports research investigating the role of N6-methyladenosine (M6A) RNA modifications in microglial dysfunction and Alzheimer's disease pathogenesis. The research will systematically map M6A RNA modification landscapes in microglia...
Award Overview New York University School of Medicine received a $712,578 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective February 1, 2026, through December 31, 2030. This prospective research study investigates the relationship between viral infections and Alzheimer's disease (AD) risk in aging populations, addressing a critical public health gap as AD prevalence is projected to triple to 13 million cases in the United States by 2050. Research Products and Services The grant funds a comprehensive prospective study utilizing three cohorts to identify viral infections associated with brain health, cognitive decline, and AD risk later in life. The research employs VirScan, a high-throughput technology using bacteriophage immunoprecipitation sequencing (PHIP-SEQ) for comprehensive serologic profiling of antiviral antibody exposure histories. This methodology overcomes significant methodological limitations in prior epidemiologic research by prospectively measuring immune responses to all known human viruses while simultaneously examining intermediate outcomes including brain health changes, cognitive function, AD-related biomarkers, and DNA methylation patterns associated with accelerated aging. The study will generate evidence-based findings on the joint and interacting effects of multiple viral infections on dementia risk, directly advancing the National Institute on Aging's mission to support research directed toward understanding and preventing Alzheimer's disease and related dementias.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $712.6k | 1/23/26 |