Project Grant RF1AG093720
Award Date 9/15/25
Completion Date 8/31/29
Dollars Obligated $3M
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
- This $342,934.65 project grant from the Department of Health and Human Services National Institutes of Health National Institute on Aging, under the Aging Research program (CFDA 93.866), will fund research into acyl chain remodeling and regional lipid dysregulation in Alzheimer's disease. The Trustees of Columbia University in the City of New York, doing business as Health Sciences Division, will analyze lipid composition in brain regions susceptible to Alzheimer's disease, such as the...
- This $461,146 federal project grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Yale University supports research to investigate the disruption of astrocytes, a key cell type in the brain, and its relationship to the development of Alzheimer's disease (AD) in animal models. The project aims to utilize novel imaging techniques to longitudinally track changes in astrocytic and neuromodulatory signaling across the cortex in awake behaving animals over the 2-year...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to determine the functional significance of microglial FOXO3 in Alzheimer's disease (AD). The $475,377 award, effective from September 5, 2025 to August 31, 2027, will be used by the awardee, The Trustees of Columbia University in the City of New York, to conduct research on the role of the FOXO3 gene and associated IFN-I signaling pathways in microglial cells and their contribution to AD...
- This Project Grant award from the National Institute on Aging's Aging Research federal grant program (CFDA 93.866) provides $871,419 to the University of Washington to conduct research on the role of microglia, the brain's immune cells, in the pathogenesis of Alzheimer's disease. The research aims to characterize molecular profiles and spatial organization of microglia across the adult age spectrum, both with and without Alzheimer's disease, through single-nucleus RNA sequencing of over 5,000...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $749,030 to The Trustees of Columbia University in the City of New York to conduct research on the mechanisms connecting calcium signaling and autophagy defects in Alzheimer's disease (AD) neurons. The goal is to understand how dysregulation of neuronal calcium (Ca2+) signaling drives impaired autophagy, a key pathological process in AD. The research will evaluate the effects of...
- The National Institute on Aging (NIA) awarded a $442,357 Project Grant under the Aging Research program (CFDA 93.866) to the Research Foundation of the City University of New York (RFCUNY) on December 15, 2024. The grant aims to elucidate the molecular mechanisms that give rise to functionally neurodegenerative microglia, the brain's primary innate immune cells, which have been implicated as major determinants of Alzheimer's disease (AD) risk. The research will leverage novel mouse models and...
- This $6,925,230 Project Grant award from the National Institutes of Health (NIH) National Institute on Aging (CFDA 93.866 - Aging Research) will support a research project at The Trustees of Columbia University in the City of New York to develop a "Multi-Organ Chart of Personalized Susceptibility to Alzheimer's Disease and Aging." The overarching goal is to use large-scale multi-omics, multi-organ biomedical data, advanced artificial intelligence/machine learning, and computational...
- This $427,625 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866). The grant was awarded to The Washington University in St. Louis to support research evaluating novel transcription factors that regulate astrocyte identity, reactivity, and their roles in the pathogenesis of Alzheimer's disease (AD) and Parkinson's disease (PD). The research aims to systematically evaluate 10 candidate transcription factors identified...
- This Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $10,847,672 to the J. David Gladstone Institutes, a non-profit biomedical research organization, to investigate the vascular-immune mechanisms underlying cerebral amyloid angiopathy (CAA) and Alzheimer's disease pathology. The research aims to elucidate the key microglial mechanisms regulating the formation of vascular CAA versus parenchymal amyloid-beta plaques, define single-cell and...
- This federal Project Grant award, valued at $1,552,000.00 and provided by the National Institute on Aging (CFDA 93.866 - Aging Research), supports a research study examining the relationship between markers of vascular and immune dysfunction, such as platelet aggregation and neutrophil levels, and their association with dementia risk and increased Alzheimer's disease (AD) biomarkers. The study, conducted by New York University School of Medicine, aims to integrate biofluid biomarker data with...