Project Grant K99MH141253
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Regents of the University of California, San Francisco a Project Grant of $832,307 under the Mental Health Research Grants program (CFDA 93.242) to investigate the genetic control of basal telencephalic development. The award, effective April 24, 2026, with a completion date of December 31, 2030, funds research aimed at identifying transcriptional and epigenetic mechanisms that control cell fate...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Regents of the University of California, San Francisco a Project Grant totaling $117,747 under the Mental Health Research Grants program (CFDA 93.242) to support research on neural computations underlying flexible behavioral control and problem-solving. The award, obligated on May 22, 2026, with a completion date of April 30, 2028, funds basic neuroscience research investigating how the brain implements...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $800,384 to The Regents of the University of California, San Francisco on March 10, 2026, under the Mental Health Research Grants program (CFDA 93.242). This award supports a four-year research project extending through December 31, 2030, focused on elucidating the molecular and functional mechanisms of prefrontal-hippocampal long-range inhibition. The research specifically investigates how...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant of $197,640 under the Mental Health Research Grants program (CFDA 93.242), effective September 1, 2025 through August 31, 2030. This award supports an early-career investigator's research into the functional consequences of schizophrenia-associated genetic variants in GRIA3, a gene encoding the GluA3 subunit of the AMPA receptor...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant totaling $196,597.00 under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco, effective July 1, 2025, through June 30, 2029. This four-year research initiative investigates the neurobiological mechanisms underlying autism spectrum disorder (ASD) phenotypes, specifically examining how a high-risk ASD gene mutation produces...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a K99/R00 Pathway to Independence grant totaling $117,263 to the University of California, Los Angeles, with an award date of May 6, 2026, and completion date of April 30, 2028, under the Mental Health Research Grants program (CFDA 93.242). This award supports a translational research initiative aimed at developing predictive models and clinical tools for risk and resilience in psychosis and bipolar spectrum...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $121,933.00 to the University of California, San Diego under the Mental Health Research Grants program (CFDA 93.242) for the period of June 1, 2025 through May 31, 2027. This research project will deliver scientific investigation into compartment-specific synaptic organization and plasticity in layer 2/3 pyramidal neurons during learning in behaving animals. The research employs cutting-edge...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $200,376 Project Grant to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242), effective April 1, 2026, through March 31, 2031. This five-year research initiative investigates intergenerational stress transmission mechanisms to understand and improve child mental health outcomes. The project examines how prenatal maternal inflammation...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $818,253 to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242) beginning July 1, 2025, and extending through April 30, 2030. This Project Grant supports a five-year research investigation examining neuromodulatory system abnormalities in late-life depression (LLD), with specific focus on the associations between structural and functional brain...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded University of California, Davis a $442,750 Project Grant under the Mental Health Research Grants program (CFDA 93.242) for the period of April 1, 2026, through March 31, 2028. The project focuses on developing novel statistical methodologies to predict individualized intervention effects in datasets characterized by clustering and longitudinal measurements. The research addresses a critical gap in precision...
The National Institute of Mental Health (NIMH) awarded $117,747.00 under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco for a K99/R00 Pathway to Independence Award project titled "Functional Characterization of Schizophrenia Related Risk Genes and Variants in Neurogenesis Using Cerebral Organoids." The award period runs from June 1, 2026, through May 31, 2028, and is conducted at UCSF's San Francisco facility. The project will deliver advanced functional genomics research aimed at systematically identifying which schizophrenia-associated genetic risk variants and genes disrupt neurogenesis during brain development. During the K99 phase, the research will employ pooled high-throughput CRISPR interference screens in neurogenic cell types derived from cerebral organoids to elucidate the roles of schizophrenia risk genes. Subsequent phases will utilize prime editing screens to assess the effects of individual schizophrenia-associated variants on neurogenesis and investigate the regulatory impact of non-coding variants on gene expression using single-cell prime editing screens. The research outputs will include novel insights into the neurodevelopmental mechanisms underlying schizophrenia, identification of potential therapeutic targets, training datasets for machine learning models focused on neurogenesis, and contributions to understanding genetic factors in other neurodevelopmental disorders.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $117.7k | 6/2/26 |