Project Grant K99DA060948

Award Date 7/15/25
Completion Date 6/30/27
Dollars Obligated $160K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
New York, USA
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The key objectives are to:

  1. Track daily changes in motivational control during inpatient heroin addiction treatment with and without fentanyl use, to understand how goal-directed control evolves with abstinence.
  2. Use the dynamic shifts in motivational control to predict changes in craving and relapse, tracked through daily ecological momentary assessments.
  3. Use a novel fMRI task to inspect motivational control neural correlates in an independent sample of opioid use disorder patients compared to healthy controls.

This research, conducted at the Icahn School of Medicine at Mount Sinai, aims to provide insights into improving treatment outcomes for individuals with opioid addiction by identifying biomarkers of recovery and relapse risk. The award period is from July 2025 to June 2027.

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