This federal Project Grant award of $265,302 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports research to investigate the neural mechanisms governing opioid use disorder (OUD) and relapse vulnerability. The research project, conducted by the Regents of the University of Minnesota, aims to map the functional and anatomical pathways between specific thalamic and striatal brain regions involved in withdrawal symptoms and cravings during early and prolonged abstinence from opioid use. The findings are expected to reveal critical insights into the neural substrates underlying relapse behavior, which could inform the development of innovative strategies for addiction treatment and prevention. This multi-year award, running from September 2024 to August 2026, represents an essential step towards the principal investigator's goal of becoming an independent addiction neuroscience researcher.
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