Project Grant R01DA059824

Award Date 8/15/24
Completion Date 5/31/29
Dollars Obligated $564K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
New York, USA
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The key products and services to be delivered include: 1) parametric and semiparametric estimators for average treatment effects, conditional average treatment effects, and optimal individualized treatment rules in multi-study, multi-outcome settings; 2) sensitivity analyses for these estimators if the untestable transport identification assumption is not met; 3) application of these methods to harmonized medication for OUD (MOUD) trials to increase statistical power; and 4) development and dissemination of user-friendly software implementing the new methods. This work aims to significantly enhance the power and information gained from data fusion, leading to improved personalized treatment of OUD and other psychiatric/substance use disorders.

The award includes a sub-grant to the Research Foundation For Mental Hygiene, Inc. (New York Psychiatric Center) to support the development of these novel data fusion techniques using clinical trial data from the NIDA Clinical Trials Network.

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