Project Grant K23DK141991
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $765,701 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, Massachusetts. The grant, titled "Mapping Mechanosensory Circuits from the Bladder to Barrington's Nucleus," will fund research to explore the neural circuits that encode bladder fullness and control urination. The project...
- This federal Project Grant award for $390,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award aims to study the impact of step therapy utilization management strategies on access to care for patients with overactive bladder (OAB), as well as evaluate alternative patient-centered treatment approaches. Key objectives include using electronic health...
- This Project Grant award of $1,429,924 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) is supporting the development of a novel, shape-changing sling for the treatment of stress urinary incontinence (SUI) in women. The goal is to create a minimally-invasive sling that can both support the urethra to achieve continence and be activated to reduce pressure on the urethra to enable complete...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to...
- This Project Grant award of $356,032 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) supports the development of a novel bladder catheterization device. The project aims to create an innovative method for bladder drainage that addresses the significant morbidity and inconvenience associated with current catheterization approaches. Over 1 million Americans, including those with neurogenic bladder conditions, require catheter use for bladder drainage. The...
- The University of California, San Francisco (UCSF) was awarded a $474,043 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to conduct research on the utilization, outcomes, and complications associated with third-line treatments for refractory overactive bladder (OAB) in older and frail older adults. The study aims to better understand how factors such as age, frailty, race, socioeconomic status, and provider experience impact the use and...
- This Project Grant award, valued at $206,132 and provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wireless, battery-free bioelectronic implant for closed-loop neuromodulation to treat detrusor sphincter dyssynergia (DSD) in individuals with spinal cord injury. The University of Houston System, the awardee, will fabricate and...
- This $2,557,146 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award was made to the Board of Regents of the Nevada System of Higher Education (UEI: WLDGTNCFFJZ3), operating through the University of Nevada, Reno, and will fund research to explore novel targets for gastrointestinal hormones and neuropeptides in the regulation of...
- This Project Grant award of $1,067,612.00, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), will fund a hybrid implementation-effectiveness trial to evaluate home neuromodulation for neurogenic bladder management in individuals with spinal cord injury. The 3-year award, effective October 1, 2025, will be conducted by the University of Texas Health Science Center at Houston (UTHealth), a comprehensive academic health university...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,516,765 to the University of California, Los Angeles (UCLA) to develop and validate an innovative near-infrared spectroscopy (NIRS) technology for the quantitative assessment of pelvic floor muscle function in patients with myofascial pelvic pain (MPP). The research aims to establish NIRS as an effective, non-invasive,...
This Project Grant award of $177,350 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to advance sacral neuromodulation (SNM) treatment for overactive bladder (OAB) through the development of objective analytics and prediction methods. The project seeks to establish non-invasive functional near-infrared spectroscopy (fNIRS) techniques to detect real-time neural responses to acute SNM reprogramming, and correlate these findings with long-term treatment success. Additionally, the project will incorporate improved tools for mapping pelvic and perineal sensations during SNM reprogramming to better quantify these sensations and optimize treatment. The award is effective from September 1, 2025 through August 31, 2030, and is being provided to Virginia Commonwealth University, a public research university in Virginia.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $177.4k | 8/29/25 |