Project Grant K23AG093224
- The National Heart, Lung, and Blood Institute awarded Icahn School of Medicine at Mount Sinai $850,669 on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate place-based drivers of health in sickle cell disease pathogenesis. The project will identify and quantify mechanisms linking neighborhood and personal exposures—including crime-related stressors, unhealthy food access, temperature, airborne particulates, and housing conditions—to clinical...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $422,500 Project Grant to Icahn School of Medicine at Mount Sinai, effective September 1, 2025 through August 31, 2027, under the Aging Research program (CFDA 93.866). This research project investigates out-of-pocket spending (OOPS) and burdensome care experiences among older adults with serious illness. The research will examine how insurance generosity—a highly modifiable policy factor varying within insurance types...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Icahn School of Medicine at Mount Sinai a Project Grant of $463,916 under the Aging Research program (CFDA 93.866) for the period September 1, 2025 through August 31, 2027. The award funds research to identify and characterize the "ankosome," a newly discovered cytoplasmic activation platform for caspase-2 (C2) that assembles in response to cytoskeletal injury. This exploratory research (R21 mechanism)...
- Federal Grant Award Summary Icahn School of Medicine at Mount Sinai received a $462,454 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective August 8, 2025 through June 30, 2027. The award supports research investigating DNA methylation (5-methylcytosine) dynamics in Down syndrome (trisomy 21) hematopoiesis and leukemia development. The primary deliverable involves mapping epigenetic...
- The National Institute for Minority Health and Health Disparities awarded Icahn School of Medicine at Mount Sinai $1,329,731 on July 19, 2026, under the Minority Health and Health Disparities Research program (CFDA 93.307) to conduct EXPAND-PC, an intervention linking prostate cancer screening with socioeconomic needs assessments and community support resources for men aged 40–69 residing in New York City Housing Authority developments. The study addresses declining prostate cancer screening...
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $704,145 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and apply computational methods for inferring the natural history of Alzheimer's disease from sparse longitudinal molecular and neuroimaging data. The recipient will develop an innovative approach that leverages temporal signal in sparse longitudinal datasets to reconstruct the timeline of Alzheimer's disease progression and...
- The National Institute of Child Health and Human Development awarded Icahn School of Medicine at Mount Sinai $249,000 on March 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to establish an independent research program investigating maternal childhood maltreatment and its effects on prenatal brain programming and infant emotion regulation outcomes. The award funds a Pathway to Independence (R00) award supporting tenure-track faculty appointments...
- The National Institute on Aging awarded Icahn School of Medicine at Mount Sinai $746,063 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate amyloid beta plaque formation and neuroinflammation in aging people with HIV. The award funds exploration of cell-specific transcriptional changes associated with early amyloid beta deposition in human brain, distinguishing compacted amyloid with early neuritic pathology from diffuse amyloid without neuritic change, and...
- The National Institute of General Medical Sciences awarded Icahn School of Medicine at Mount Sinai $462,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to advance spatial imaging frameworks that reveal how non-coding RNAs organize within the nucleus across developmental and environmental contexts. The research establishes three interconnected themes. Theme 1 extends RNA MERFISH to profile small non-coding RNAs by incorporating enzymatic...
- The National Institute of Environmental Health Sciences awarded Icahn School of Medicine at Mount Sinai $1.42 million on September 17, 2025, under the Environmental Health program (CFDA 93.113) to investigate the urban-social exposome on maternal depression. The research investigates how stress, built environment factors, and urban exposures—including particulate matter (PM2.5)—act as causal factors in maternal depression through effects on key biological pathways such as inflammation, hormone...
The Department of Health and Human Services National Institutes of Health Office of the Director awarded Icahn School of Medicine at Mount Sinai $165,509 on August 5, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to conduct a mixed-methods study examining exposure to incarceration among community-dwelling older adults and its effects on health, mechanisms of harm, and sources of resilience. The research addresses three specific aims: describing health effects of exposure to incarceration at personal, family, and neighborhood levels among older adults and exploring mechanisms and resilience factors through interviews; estimating associations between personal incarceration and self-reported health, functional status, and cumulative biological risk in a nationally representative sample while testing individual-level mediators and effect modifiers; and estimating associations between living in high-incarceration census tracts and self-reported health, functional status, and cumulative biological risk while testing population-level mediators and effect modifiers. Findings will establish foundation for subsequent R21 pilot and R01 funding for a community-partnered intervention to mitigate health harms of incarceration exposure among older adults. Performance occurs at the recipient's location in New York, New York, with a period of performance running through May 31, 2031. The award is classified as a Project Grant, a competitive assistance type reviewed for scientific and technical merit by peer review and for program relevance by the National Institute on Aging's national advisory council.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $165.5k | 8/4/26 |