Project Grant K23AG093103
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Southern California $4,055,366 under the Aging Research program (CFDA 93.866) to conduct a four-year research project examining the impact of circulating endocrine disrupting toxicants on cognition, brain activity, and Alzheimer's disease (AD) biomarkers across the menopausal transition. The project, which commenced on September 15, 2025, and concludes August 31, 2029, addresses a critical gap...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Columbia University's Health Sciences Division a $244,023 Project Grant effective August 1, 2025, through July 31, 2028, under the Aging Research program (CFDA 93.866). This research project investigates the social mechanisms underlying sex differences in Alzheimer's Disease (AD), with particular focus on how societal barriers experienced by women—especially Black women—contribute to disparate cognitive health outcomes and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $429,000 Project Grant under the Aging Research program (CFDA 93.866) to The Regents of the University of Colorado, doing business as University of Colorado-Denver, effective January 1, 2026, through December 31, 2027. The grant funds research aimed at defining the role of decreased estradiol in modulating crotonylation of myofilament proteins in aged female hearts. Specifically, the research project seeks to...
- Federal Grant Award Summary Northwestern University received a $198,164 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) awarded on September 27, 2025, with completion targeted for May 31, 2028. The award funds research investigating sex-specific hypothalamic pathology and immune infiltration in Alzheimer's Disease (AD), addressing the critical gap that nearly two-thirds of AD cases occur in females despite limited understanding of the...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of Colorado-Denver a Project Grant of $442,485 under the Aging Research program (CFDA 93.866) for the period June 1, 2026, through May 31, 2028. The research project investigates selective vulnerability of the locus coeruleus and paraventricular nucleus of the hypothalamus to Herpes Simplex Virus Type 1 (HSV-1) infection in Alzheimer's disease (AD) progression. The primary deliverables include research...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $174,672 Project Grant to the University of California, Santa Barbara on March 18, 2026, under the Aging Research program (CFDA 93.866). This research initiative, titled "Elucidating the Influence of Ovarian Aging and Endocrine Shifts on Spatial Navigation, as an Early Diagnostic Target for Alzheimer's Disease," will produce scientific research aimed at establishing the relationship between ovarian...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $1.30 million Project Grant to the University of Delaware, effective February 1, 2026 through January 31, 2031, under the Aging Research program (CFDA 93.866). This five-year research project examines sympathetic nervous system activation and cardiovascular function changes during the menopausal transition in women. The research addresses a critical knowledge gap regarding how declining estradiol and increasing...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Marquette University $424,875 under the Aging Research program (CFDA 93.866) on June 15, 2026, to conduct a two-year research project investigating the influence of ovarian hormones and age on prefrontal encoding of episodic fear memories. The research addresses a significant health gap related to menopause and age-related cognitive decline, particularly concerning increased risk for affective disorders and Alzheimer's...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $424,371 to the University of Michigan's Office of Research and Sponsored Projects on February 15, 2026, under the Aging Research program (CFDA 93.866). The two-year project, scheduled for completion on February 14, 2028, supports research investigating how hormone contraceptive (HC) exposure across the female lifespan protects against Alzheimer's disease (AD) progression. The research team...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $2.33 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2029. The award funds research evaluating neuroimmune mechanisms and therapeutic targeting potential of the luteinizing hormone/chorionic gonadotropin (LH/CG) receptor in menopausal and Alzheimer's disease-affected brains....
Award Details: The National Institute on Aging (NIA) awarded a Project Grant totaling $189,963 to The Regents of The University of Colorado, doing business as University of Colorado-Denver, with an award date of July 1, 2026, and a completion date of April 30, 2031. This award is funded under the Aging Research program (CFDA 93.866). Research Scope and Deliverables: Dr. Carlisle will conduct a five-year research study investigating the contributions of biological sex and sex hormones to cognitive reserve and Alzheimer's disease (AD) risk across the cognitive spectrum. The project will examine why females—despite greater neuroprotective estrogen exposure—face higher AD risk and greater memory decline despite baseline cognitive advantages. The research will evaluate the dynamic changes in cognitive reserve across the lifespan in males and females, with particular focus on the perimenopause transition as a neurologically vulnerable window for early AD-associated pathology initiation. The study will generate empirical data and analysis on how estradiol-based signaling pathways and ovarian hormone changes during midlife affect cognitive reserve trajectories and AD progression, with findings intended to inform understanding of sex-based differences in AD vulnerability and potential interventions targeting critical hormonal periods.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $190.0k | 6/29/26 |