Project Grant K08HS029515
- This Project Grant award from the National Center for Advancing Translational Sciences (CFDA 93.350) provides $159,103 to investigate the experiences of parents seeking emergency care for their injured children with special healthcare needs. The study will engage at least 35 family caregivers to gather qualitative data on factors contributing to poor care quality and hospital complications for this population. The project aims to elucidate the mechanisms behind adverse outcomes in injured...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Children's Hospital of Philadelphia a $180,174 Project Grant effective August 1, 2025, through July 31, 2030, under the Cardiovascular Diseases Research program (CFDA 93.837). This award supports the development of an improved framework for designing next-generation pediatric acute respiratory distress syndrome (ARDS) clinical trials. The research addresses limitations in current trial methodologies...
- This Project Grant award, funded by the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program, supports a comprehensive $398,972 study on improving healthcare quality and equity for newborns with prenatal substance exposure. The study, conducted by the University of California, Davis in collaboration with the Better Outcomes through Research for Newborns (BORN) network and the EMPOWER stakeholder group, aims to:...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Boston Children's Hospital a $1.99 million Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective September 1, 2025, through August 31, 2027. The award funds the TETRIS (Trends and Epidemiology Through Real-Time Injury Surveillance) initiative, which develops a novel pediatric injury surveillance system utilizing...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Oregon Health & Science University a $1.63 million Project Grant on September 19, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct the Pediatric Prehospital Ventilation Trial (PEDI-VENT). This ancillary study will leverage existing infrastructure from the parent PEDI-PART clinical trial operating across 60+ Emergency Medical Services (EMS) agencies to analyze pediatric...
- Federal Grant Award Summary Boston Children's Hospital received a $279,644 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with completion scheduled for August 31, 2027. The grant funds research to develop and validate time to return of spontaneous circulation (ROSC) as a novel primary outcome measure for pediatric in-hospital cardiac arrest (P-IHCA) clinical trials. The research...
- Grant Award Summary Boston Children's Hospital received a $2.40 million Project Grant from the Health Resources and Services Administration (HRSA), Bureau of Health Professionals under the Mental and Behavioral Health Education and Training Grants program (CFDA 93.732), awarded July 1, 2025 through June 30, 2030. The award supports the expansion of the pediatric addiction medicine workforce by increasing the number of physicians trained to prevent and treat substance use disorders (SUDs) in...
- This Project Grant award from the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program will provide $275,000 in funding to the University of Texas Health Science Center at Houston from August 1, 2024 to July 31, 2026. The project aims to develop and test strategies to increase implementation of evidence-based interventions through collaboration with patient advocacy groups in the areas of juvenile idiopathic...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of Pittsburgh a $238,500 Project Grant effective May 1, 2026 through April 30, 2028, under the Cardiovascular Diseases Research program (CFDA 93.837). This award supports research to develop and validate natural language processing (NLP) and machine learning (ML) algorithms that enhance prehospital triage decision-making by analyzing free-text clinical observations. The project...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $427,256 Project Grant (CFDA 93.837 – Cardiovascular Diseases Research) to Columbia University's Health Sciences Division on September 15, 2025, to conduct a pilot feasibility study supporting development of a definitive randomized controlled trial evaluating bilevel positive airway pressure (BPAP) as a second-line therapy for severe pediatric asthma exacerbations in emergency department settings. The...
IMPROVING RISK PREDICTION FOR CHILDREN SEEKING EMERGENCY MEDICAL SERVICES (EMS) CARE WITH NON-EMERGENT COMPLAINTS - ABSTRACT: APPROXIMATELY 1.6 MILLION CHILDREN ACCESS THE HEALTHCARE SYSTEM THROUGH EMERGENCY MEDICAL SERVICES (EMS) EACH YEAR IN THE U.S. DESPITE AN ABSENCE OF VALIDATED EMS TRIAGE TOOLS, 30% OF ALL CHILDREN ARE LEFT AT THE SCENE, WHILE MANY LOW ACUITY CHILDREN ARE TRANSPORTED TO AN EMERGENCY DEPARTMENT (ED) UNNECESSARILY. THIS NON-STANDARDIZED EMS APPROACH RESULTS IN BOTH UNDER-TRIAGE AND OVER-TRIAGE OF CHILDREN. THE USE OF EMS FOR NON-EMERGENT COMPLAINTS IS UNSAFE BECAUSE IT CAUSES DELAYS IN EMS RESPONSE TIMES FOR OTHER PATIENTS AND EXACERBATES ED OVERCROWDING. CURRENT EMS TRIAGE TOOLS WERE NOT DESIGNED TO IDENTIFY CHILDREN WHO CAN BE SAFELY MANAGED WITHOUT EMERGENT TRANSPORT TO THE ED. THERE IS AN URGENT NEED FOR A PEDIATRIC EMS RISK ASSESSMENT TOOL (SIMILAR TO THE EMERGENCY SEVERITY INDEX [ESI] ED TRIAGE SCORE DEVELOPED WITH SUPPORT FROM THE AGENCY FOR HEALTHCARE RESEARCH AND QUALITY [AHRQ]). THE PEDIATRIC OBSERVATION PRIORITY SCORE (POPS) WAS DEVELOPED TO IDENTIFY CHILDREN AT LOW RISK OF DETERIORATION IN EMERGENCY SETTINGS. POPS HAS BEEN VALIDATED IN EDS WITH MODERATE/EXCELLENT INTER-RATER RELIABILITY BETWEEN DIFFERENT HEALTHCARE PROFESSIONALS AND IS USED IN SOME EMS AGENCIES IN THE UNITED KINGDOM. THE ACCEPTABILITY AND ACCURACY OF THE POPS TOOL IN EMS IS UNKNOWN. THE OVERALL GOAL OF THIS PROPOSAL IS TO REFINE AND PILOT-TEST THE POPS TOOL FOR USE BY EMS CLINICIANS. THIS WILL BE ACHIEVED THROUGH THE FOLLOWING SPECIFIC AIMS: (1) IDENTIFY FACTORS ASSOCIATED WITH UNDER- TRIAGE FOR CHILDREN NOT TRANSPORTED BY EMS; (2) OPTIMIZE THE ACCEPTABILITY, APPROPRIATENESS, AND FEASIBILITY OF THE POPS TOOL WITH CLINICAL END-USERS; AND (3) ASSESS THE REFINED POPS TOOL THROUGH SIMULATION AND FIELD PILOT STUDIES. AIM 1 WILL BE CONDUCTED IN A MULTISITE RETROSPECTIVE ANALYSIS LINKING EMS RECORDS AND MEDICAID CLAIMS DATA (A HIGH-RISK POPULATION). THE POPS TOOL WILL BE REFINED BY INCORPORATING FACTORS FOUND TO BE ASSOCIATED WITH UNDER-TRIAGE. AIM 2 WILL BE ADDRESSED USING A MIXED-METHODS APPROACH WITH EMS CLINICIANS. THE POPS TOOL WILL BE REFINED AND ITERATIVELY ASSESSED BEFORE PILOT TESTING. AIM 3 WILL INVOLVE ASSESSING THE REFINED POPS TOOL IN SIMULATIONS WITH EMS CLINICIANS AND A FEASIBILITY FIELD PILOT TEST LINKING POPS SCORES WITH PATIENT OUTCOMES. THESE STUDIES WILL GENERATE PRELIMINARY DATA ON TOOL ACCURACY AND UNDER AND OVER-TRIAGE RATES, LEADING TO A NATIONAL EFFECTIVENESS TRIAL OF THE REFINED POPS TOOL. A VALIDATED PEDIATRIC SCREENING TOOL WOULD ENABLE URGENTLY NEEDED STUDIES OF EMS INNOVATIONS (INCLUDING TREATMENT IN PLACE, TELEMEDICINE, AND INTEGRATION OF PRIMARY CARE) FOR CHILDREN, AN AHRQ PRIORITY POPULATION. THE PRINCIPAL INVESTIGATOR, DR. CALEB WARD, IS AN EARLY CAREER PHYSICIAN-SCIENTIST WITH A STRONG CLINICAL BACKGROUND IN PEDIATRICS, EMERGENCY MEDICINE, AND EMS. THIS AWARD WILL FOSTER HIS DEVELOPMENT AS A RESEARCHER WITH CONTENT EXPERTISE IN LARGE DATABASE ANALYTICS, MULTISITE EMS RESEARCH, AND IMPLEMENTATION SCIENCE. A MENTORSHIP TEAM WITH EXPERTISE IN THESE CONTENT AREAS WILL SUPPORT DR. WARD AS HE COMPLETES THESE RESEARCH AIMS AND RELATED CAREER DEVELOPMENT ACTIVITIES TO ENSURE HIS TRANSITION TO RESEARCH INDEPENDENCE.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $142.5k | 9/12/25 | ||
| Not listed | $0 | 12/23/24 | ||
| Not listed | $142.0k | 7/25/24 | ||
| Not listed | $142.0k | 7/25/24 |