Project Grant K08AR083508
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
- This $465,663 Project Grant was awarded on May 6, 2025 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports research to optimize the bone surface targeting of therapeutic antibodies for the treatment of osteoporosis, a common bone disease affecting 10 million U.S. adults. The project aims to increase the local concentration and efficacy of osteoporosis...
- This $219,609 project grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is aimed at developing a method to assess mechanical failure of bone matrix using in vitro cell culture. The primary goal is to overcome the current challenge of requiring whole mouse bone specimens to detect changes in bone matrix mechanical properties, by using micropillars generated from...
- This $663,901 Project Grant was awarded on September 1, 2025 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports Emory University's research to understand how the gut microbiome and T-cells influence fracture healing. The project aims to investigate how gut bacteria and immune cells, particularly Th17 cells, can be leveraged to improve fracture repair and...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), provides $688,634.00 in funding to The Hospital For Special Surgery Fund, Inc. (dba HSS Foundation) from December 1, 2024 to November 30, 2029. The award supports research to investigate the mechanisms by which the constitutive type-I interferon (IFN-I) response suppresses osteoblastogenesis and bone formation, especially in the context of inflammatory conditions like rheumatoid...
- The Project Grant award for $651,514 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to evaluate how bone quality metrics measured from digital tomosynthesis images of the wrist can change over time in postmenopausal breast cancer patients receiving aromatase inhibitor therapy. The research is being conducted through a collaborative partnership between Henry Ford...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to identify myeloid progenitors that maintain cortical bone mass with age and characterize factors that promote coupling within cortical bone. The $375,100 award, active from Sep 20, 2024 to Aug 31, 2026, supports research at the University of Minnesota to address the significant impact of...
- This Project Grant award of $169,344 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research at the University of California, Davis to investigate the role of inflammation and immunomodulation in fracture healing in the context of polytrauma. The key objectives are to: (1) characterize the upregulation of inflammatory cytokines and innate...
- This Project Grant award of $139,895.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) will support research into the link between inflammatory arthritis and the development of cardiovascular disease. The key objectives are to investigate whether "trained immunity" - the phenomenon where innate immune cells become reprogrammed to respond more efficiently to a...
- This federal Project Grant award of $685,866.00 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The goal of this 5-year project is to leverage context-specific expression quantitative trait loci (eQTLs) to identify potential causal genes underlying genome-wide association study (GWAS) findings related to bone mineral density (BMD) and...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) provides $177,120 to evaluate the predictive validity of the Fracture Risk Assessment Tool (FRAX) for 10-year risk of major osteoporotic fractures and hip fractures in persons with rheumatoid arthritis (RA). The project aims to compare FRAX predictive performance in RA populations to the general population, including analyses by sex, race/ethnicity, and age. The research will be conducted by the Augusta University Research Institute, Inc. located in Augusta, GA. The award period is from September 1, 2025 to August 31, 2030. This research seeks to optimize fracture risk prediction and guide therapeutic decisions for individuals with RA, a group at heightened risk of debilitating fragility fractures.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $177.1k | 8/27/25 |