This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $306,858 to Mira Medical, LLC to develop a machine learning framework, called the Forearm Fracture AI-Driven Recommendation System (FFAIRS), to improve the management of pediatric forearm fractures. The goal is to leverage AI and machine learning to generate treatment...
The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a $299,428 Project Grant to WNT Scientific LLC to develop an innovative medical device to treat nonunion fractures in older adults. The device is a biodegradable, controlled-release material designed to promote fracture healing by stimulating angiogenesis (blood vessel formation), which is impaired in elderly patients due to chronic inflammation. The awarded project aims to commercialize this...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under CFDA Program 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research, is for the development of a "Smart Cavity Creator Drill for Lumbar Interbody Fusion". The $830,712 award, effective from April 1, 2025 to March 31, 2027, aims to commercialize a novel lumbar interbody fusion technology that uses a small approach channel to create a large cavity in...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $608,358 to investigate the role of the neuropeptide calcitonin gene-related peptide (CGRP) in bone healing and chronic pain following bone fractures. The research aims to test the hypothesis that CGRP signaling is beneficial for bone healing but contributes to nociceptive pain...
This Project Grant award, ID R21AR084126, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The $783,176 award supports research to develop and validate a quantitative spine imaging methodology using photon-counting detector CT (PCD-CT) technology to comprehensively characterize bone quality, including cortical and trabecular microstructures, in patients with...
This federal Project Grant award, valued at $626,879.00, was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The research aims to explore a novel mouse model of large-scale bone regeneration to unravel the cellular and molecular mechanisms governing the initiation and coordination of bone repair following extensive injuries. Specifically, the research will...
This $162,500 project grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to generate preliminary data on the relationships between mechanical loading, zinc homeostasis, and bone fracture healing. The award recipient, The Trustees of the University of Pennsylvania, will conduct in vivo studies using a rat femoral osteotomy model to investigate how the...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $388,960 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to the Medstar Health Research Institute Inc. to evaluate the use of machine learning algorithms to analyze accelerometry data and gain insights into functional recovery of the upper extremity following distal radius fracture repair. The project aims to train algorithms to differentiate functional versus...
This federal Project Grant award of $456,808.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting the development of advanced mass spectrometry imaging (MSI) technologies to spatially visualize proteins and glycans in musculoskeletal tissues. The primary awardee, the Buck Institute for Research on Aging, is collaborating with researchers at the University of...
This Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to develop a novel gene therapy for bone healing. The $454,050 award, effective February 1, 2025 through January 31, 2030, will support research to create an adeno-associated virus (AAV)-based gene therapy that delivers bone morphogenetic protein-2 (BMP-2) to heal critical-size bone...