The National Institutes of Health (NIH) Office of the Director awarded a $1,271,280 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Allen Institute in Seattle, WA. The award, spanning September 2024 to September 2027, aims to develop two "exa-scale" (extremely high-throughput) tissue readout methods to transform the study of the brain. The first method will enable highly multiplexed molecular mapping of individual proteins across entire brains at the...
The National Institutes of Health (NIH) Office of the Director awarded a $1,345,424 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Regents of the University of Michigan. The grant, effective September 10, 2024 through September 9, 2027, aims to develop a novel genetically encoded "protein ticker tape" system that enables long-term, brain-wide recording of single-cell physiology in live mice without external interfacing. The technology will leverage...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,461,383 Cooperative Agreement under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to The Broad Institute, Inc. The award, effective August 31, 2024 through July 31, 2027, will fund the development of innovative technologies to systematically map the projections of thousands of midbrain dopaminergic neurons across the marmoset brain and quantify...
This three-year, $4.45 million project grant from the National Institutes of Health's Trans-NIH Research Support program will fund research into unraveling the developmental relationship between gene expression and long-range cortical projections in neurons. The Allen Institute will receive the funding to improve the resolution and scale of in situ sequencing-based neuroanatomical approaches. This will generate an unprecedented view of how gene expression correlates with and influences the...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
The National Institute of Neurological Disorders and Stroke (NINDS), through its Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $578,701 project grant to the University of California, Los Angeles (UCLA) on June 16, 2025. The goal of this 5-year project is to develop a near-infrared confocal squeezed light-field microscopy (SLIM) system capable of kilohertz volumetric imaging of neuronal action potentials in 3D. This technology is intended to...
The Johns Hopkins University was awarded a $2,008,605 Project Grant under the National Institute of Neurological Disorders and Stroke's 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funding will support the development of an "Autonomous Rapidly Adaptive Multiphoton Microscope for Neural Recording and Stimulation." This adaptive multiphoton microscope system will leverage hybrid volumetric scanning,...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
This $1,999,635 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke (NIH NINDS) will fund research into understanding feedforward and feedback signaling between neuronal populations. The grant was awarded to Albert Einstein College of Medicine on March 15, 2022 for a period ending February 28, 2025. The project aims to advance understanding of how feedforward and feedback signaling work together in the visual system by analyzing...
The Regents of the University of Michigan received a $137,586 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funds the development of a reconfigurable neural interface platform that can integrate multiple sensor modalities, including electrophysiological recording, neurostimulation, and physiochemical...