Project Grant 2638621
- The National Institute of General Medical Sciences (NIGMS) of the Department of Health and Human Services awarded the University of California, Berkeley $287,221 in project grant funding on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). The award funds research into the molecular dynamics of biomolecules and their interactions, with emphasis on fusing biophysics and machine learning approaches. The work develops rigorous computational models and...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of California, San Diego $800,000 on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to systematically identify, functionally characterize, and solve high-resolution structures of RNA tertiary motifs in human cells. The research addresses a significant gap in understanding human gene regulation by using innovative chemical probing technology to discover and visualize...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Brandeis University $370,052 on August 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate how intrinsically disordered regions in proteins regulate the search and binding of heterochromatin-associated proteins in living cells. The research aims to determine how dynamic recruitment and retention of histone H3 lysine 9 methylation-binding proteins establish stable and heritable gene...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of California, Berkeley $951,106 on June 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate how microtubule-associated proteins regulate kinesin motor proteins in intracellular transport. The research combines structural biology, biophysics, and protein engineering to determine how specific microtubule-associated proteins (tau, MAP7, MAP9, and doublecortin) control...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $300,000 to University of California, Berkeley on July 15, 2026, for collaborative research engineering synthetic multi-kingdom anaerobic communities to produce volatile fatty acids from biomass. The award is a Project Grant under the Biological Sciences program (CFDA 47.074). Performance occurs at Berkeley, California, with a completion date of June 30, 2029. No sub-recipients are planned for this award.
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $967,237 to the University of California, Santa Barbara on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to establish the quantitative physical principles governing mesoscale arginine-glycine-glycine (RGG) peptide and RNA interactions using integrated approaches combining single-molecule mechanical manipulation, bulk phase behavior analysis, and computational modeling. The research...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1.2 million to the University of California, Davis on July 15, 2026 under the Biological Sciences program (CFDA 47.074) to fund research on gene-specific nuclear messenger ribonucleoprotein (mRNP) assembly and quality control. The project investigates how information encoded in genes is transported within cells to direct protein production at appropriate times and locations. The research focuses on defining...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of California, Santa Barbara $1,201,130 on June 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the mechanisms of peroxisomal membrane protein biogenesis across animal, plant, and fungal cells. The project addresses how cells synthesize, target, and maintain proteins within peroxisome membranes, which sequester metabolic enzymes and their toxic byproducts to protect...
- The University of California, Los Angeles was awarded a $763,871 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences. The grant supports research titled "Packaging, Targeting, and Replication of Virus-Derived RNA Replicons" from July 1, 2021 to June 30, 2024. The grant funds basic research into biological sciences as part of the NSF's Biological Sciences program (CFDA 47.074). Specifically, the university will conduct research on packaging,...
- The National Science Foundation Division of Physics awarded $570,000 to the University of California, Berkeley on July 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to investigate environment-driven active matter inspired by influenza A virus behavior. The research establishes theoretical and experimental frameworks for understanding how nanoscale particles navigate dense, complex environments without internal energy sources. Investigators will examine how influenza...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of California, Berkeley $180,426 on July 1, 2026, under the Biological Sciences program (CFDA 47.074) to structurally characterize the nucleocapsid-mediated packaging of the SARS-CoV-2 genome using nuclear magnetic resonance methods. The research integrates magic angle spinning (MAS) and dynamic nuclear polarization (DNP) NMR techniques to overcome current challenges in studying complex heterogeneous viral genome ribonuclear particles and to provide atomic-level knowledge of the structure and dynamics of the SARS-CoV-2 nucleocapsid protein and its organization in assemblies with genomic RNA. The methodological framework developed through this work will establish integrative magnetic resonance-based protocols applicable to structural biology, biochemistry, physical chemistry, biotechnology, and pharmacology research communities. The project includes an educational component providing training in state-of-the-art experimental methods to students at all levels and embedding opportunities for laboratory personnel at the principal investigator, co-principal investigator, and industrial collaborator sites to enhance STEM workforce development. Performance occurs in Berkeley, California. The period of performance runs from July 1, 2026, through March 31, 2027. The award is classified as a Project Grant under the Biological Sciences program, which supports basic research to advance scientific knowledge and strengthen the Nation's scientific enterprise.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $180.4k | 8/4/26 |