This three-year, $321,668 Project Grant from the National Science Foundation's Division of Emerging Frontiers will fund research into the impact of horizontal gene transfer on genetic evolution in bacteria. Awarded to Yale University on February 1, 2022 and set to be completed by January 31, 2025, this grant supports work under the Biological Sciences program (CFDA 47.074). Specifically, the grant will further the biological sciences and understanding of major problems by funding three aims....
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 will fund a 3-year postdoctoral fellowship to research the adaptive response of bacteria to bacteriophage infection and high hydrostatic pressure. The fellow will develop novel fluorescence microscopy techniques to quantify bacterial growth, cell size, and morphology under these environmental stressors using model organisms E. coli, P. aeruginosa, and S. piezotolerans. The project...
This $487,135 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research on the diversity and evolution of extremophilic microbial eukaryotes found in geothermal spring systems. The research aims to document the biodiversity of these single-celled protists, describe new species, and improve understanding of the tree of life. Key activities include single-cell profiling, culturing, and microscopy-based analyses to infer...
This National Science Foundation Project Grant award of $776,213 provides funding over five years from January 2023 through December 2027 for research and educational efforts focused on developing novel statistical methods to detect parallel evolution in microbiome metagenomic data. The grant is awarded under the Biological Sciences program (CFDA 47.074) to support basic biological research that strengthens the nation's scientific enterprise. Specifically, the University of California, Los...
This three-year, $409,923 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of genomic algorithms and statistical models to study natural gene transfer in transformable bacteria at the University of Wisconsin-Madison. The university will collaborate with partners to generate genome-scale statistical algorithms and computational tools for analyzing molecular and biological drivers of gene transfer events during natural...
This three-year, $673,000 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research into the role of ecological interactions in diversification among coexisting microbial species. The University of California, Irvine will study how commensal interactions, where one species benefits while the other is unaffected, influence the formation of new bacterial species in microbial communities. Researchers will culture bacteria in a commensal...
This three-year National Science Foundation project grant of $799,491 will fund research into the role of horizontal gene transfer in the evolution of antibiotic resistance among bacterial communities. The University of Washington will receive the funding to conduct three related research aims. First, the researchers will propagate communities of Escherichia coli, Salmonella enterica, and Klebsiella pneumoniae bacteria and monitor the evolution of a plasmid-borne gene conferring beta-lactam...
This federal Project Grant award, valued at $961,999.00, was provided by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program. The grant will support research to elucidate the early origins and evolution of Asgard archaea, a group of microbes that provide insights into the diversification of life on Earth, including the origin of eukaryotes. The project will collect and analyze microbiome samples from hot springs in the western United States, with the goal of...
The federal Project Grant award, valued at $697,510.00 and funded by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program, aims to improve, validate, and interpret amino acid substitution models for protein evolution. The research will enhance understanding of how substitutions of amino acids in proteins impact their form and function, which is critical for reconstructing the evolutionary history of proteins and advancing phylogenetic inference. The project, with a...
This $470,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to the University of Pittsburgh supports an integrated research-education program called "BIORETS: Creating Communities of Practice to Translate Microbial Evolution in Action Research to the Classroom." Over 3 years, the program will engage 18 high school and middle school science teachers in authentic microbiology research to understand how bacteria adaptively...