The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $750,000 Project Grant to The Washington University in St. Louis to support research and training related to understanding how metabolic burdens affect microbial cells used in biotechnology applications. The 3-year award, which commenced on August 15, 2023, will enable the Principal Investigator to acquire expertise in modern metabolomics and gene editing techniques, and apply these methods to analyze a model industrial yeast chassis for the biosynthesis of natural products. The research aims to uncover the underlying causes, extent, and effects of metabolic burdens that lead to metabolic or evolutionary changes in microbial cells, in order to facilitate the design and control of microbial pathways for effective bioproduction. The project will also train graduate students, undergraduates, and high school students in interdisciplinary biotechnology research, and involve collaborations with Lincoln University, a Historically Black College and University.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $750.0k | 7/26/23 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
WU240472S | Lincoln University | Project Grant 2320104 | $48.5k | 4/10/24 |