The Pennsylvania State University was awarded a $380,000 Project Grant from the National Science Foundation on February 15, 2021 to complete work by January 31, 2024. The grant funds a collaborative research effort titled "Designing a Minimized Genome Cyanobacterial Chassis for Efficient Bioproduction" under the NSF's Biological Sciences program (CFDA 47.074). The research aims to promote progress in the biological sciences by increasing scientific knowledge and enhancing understanding...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $750,000 Project Grant to The Washington University in St. Louis to support research and training related to understanding how metabolic burdens affect microbial cells used in biotechnology applications. The 3-year award, which commenced on August 15, 2023, will enable the Principal Investigator to acquire expertise in modern metabolomics and gene editing techniques, and apply these methods to...
The National Science Foundation awarded a $514,999 Project Grant to the President and Fellows of Harvard College from February 15, 2021 through January 31, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research to design a minimized genome cyanobacterial chassis for efficient bioproduction. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through increasing...
The National Science Foundation (NSF) awarded a $800,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Washington University's Office of Sponsored Research Services Division. The 3-year project aims to investigate the metabolic cooperation between a phototrophic bacterium and a methanogenic archaeon, and how this "syntrophic" interaction influences methane production and the nitrogen cycle in anoxic environments. The research will shed light on how these...
This National Science Foundation (NSF) Project Grant award under CFDA 47.074 Biological Sciences aims to deepen the understanding and improve the production of natural, renewable fibers derived from the extracellular polysaccharide (EPS) of the cyanobacterium Anabaena 33047. The $1,170,000 award, spanning 9/1/2024 to 8/31/2027, will use a combination of systems biology and synthetic biology approaches to identify and manipulate the genetic and metabolic factors controlling EPS production. This...
This $1,373,044 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the Massachusetts Institute of Technology to develop microbial strains with minimal genomes for integrated bioprocessing using supercritical carbon dioxide. The goal is to elucidate the genotype-phenotype relationship of tolerance to supercritical CO2 for a selected microorganism and construct a reduced genome strain displaying the desired tolerance phenotype....
This $656,664 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at Miami University from August 2022 through July 2025 to develop microbial strains with minimal genomes for integrated bioprocessing applications. The goal is to elucidate the genotype-phenotype relationship of tolerance to supercritical carbon dioxide in a selected microorganism using a reduced genome approach. Researchers will construct transposon libraries to...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $1,000,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Madison. The 3-year grant, effective September 1, 2023, supports a collaborative research project between the University of Wisconsin-Madison and members of the Department of Energy's Agile Biofoundry to investigate bacterial transporters and engineer them for superior properties in...
The National Science Foundation Division of Integrative Organismal Systems awarded a $206,320 Project Grant to the Donald Danforth Plant Science Center for the period of May 1, 2022 through April 30, 2023. The grant supports collaborative research to develop an artificial chromosome system in Chlamydomonas based on CENH3 tethering under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...
This Project Grant award from the National Science Foundation (NSF) Division of Integrative Organismal Systems, under the Biological Sciences program (CFDA 47.074), provides $135,529 to the University of Wisconsin - Madison to further develop genetic manipulation techniques for the cyanobacterium Prochlorococcus. Prochlorococcus is the most abundant photosynthetic organism in the ocean, contributing substantially to global carbon fixation. The key objectives are to optimize methods for...