Project Grant 2317112
Award Date
8/1/23
Completion Date
7/31/26
Dollars Obligated
$950K
Federal Agency
Division of Molecular and Cellular Biosciences
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
New York, NY 10065, USA
Similar Awards
The National Science Foundation (NSF) awarded a $1,199,997 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Colorado-Denver. The grant will fund research to improve understanding of the mechanisms underlying messenger RNA (mRNA) localization and translation, and develop machine learning models to better predict protein production from mRNA. The project will apply recent advancements in RNA sequencing technology to study how factors like tRNA abundance and...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $414,164 Project Grant under the Biological Sciences CFDA program to the University of Illinois at Chicago. This 3-year grant, awarded on August 15, 2023, will support research to study how enzymes in intermediary metabolism interact with and bind to RNA molecules. The project aims to gain a greater understanding of these protein-RNA interactions and their effects on regulating cellular activities,...
The National Science Foundation (NSF) awarded a $700,000 Project Grant under the Biological Sciences (CFDA 47.074) program to the Research Foundation of the City University of New York (RFCUNY) operating as Rfcuny - Brooklyn College. This 3-year grant, effective August 15, 2024, supports research to elucidate the epigenetic mechanisms by which prions (self-replicating proteins) impact cellular functions and environmental adaptation in baker's yeast. The research objectives include mapping...
This Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences CFDA program (47.074), will investigate a novel regulatory mechanism called "RNA buffering" that maintains messenger RNA (mRNA) levels despite changes in synthesis and decay rates. The $749,978 project at the University of Utah will explore the protein-protein and protein-RNA interactions involved in this process, which challenges...
This National Science Foundation (NSF) Biological Sciences program grant to Yale University, totaling $940,000 over 3 years beginning March 1, 2024, aims to systematically identify features of human and viral messenger RNAs (mRNAs) that regulate protein production. The project will employ a massively parallel reporter assay to quantify the impact of RNA modifications, structured RNA elements, and cell-specific factors on mRNA translation. Insights gained will provide a comprehensive...
The National Science Foundation awarded a $1,109,203 Project Grant to The Research Foundation For The State University Of New York to elucidate the role of protein arginine methylation in regulating RNA-binding protein function from May 2021 through April 2025. This award supports research under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the Nation's scientific enterprise through increasing scientific knowledge and...
This Project Grant award for $372,880 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. The objective of the research project is to understand how cells regulate protein synthesis in response to environmental stressors, with a focus on the role of the essential translation initiation factor eIF2. The proposed...
The National Science Foundation (NSF) awarded a 5-year, $520,000 CAREER grant to the University of Colorado-Denver under the Biological Sciences program (CFDA 47.074) to research mechanisms of nonsense-mediated RNA decay (NMD) evasion by endogenous and viral transcripts. The project aims to leverage evolutionary analysis, molecular biology, and genomics to identify signals that allow physiological RNAs resembling aberrant RNAs to escape NMD quality control. It will also engage 8th-9th grade...
This $1,220,400 Project Grant awarded by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences supports a collaborative research project between investigators in the U.S. and U.K. to better understand the regulatory mechanisms controlling mammalian gene expression. The project, funded through NSF's Biological Sciences program (CFDA 47.074), aims to define the roles of different DNA regulatory elements and how they work together to precisely control gene expression....
The University of Utah will receive $492,516 from the National Science Foundation Division of Molecular and Cellular Biosciences under a three-year Project Grant award titled "Role of Electric Fields and a Dynamic Local Environment in Protein-RNA Molecular Recognition." The grant funds basic research from August 1, 2021 to July 31, 2024 to advance understanding of major problems in the biological sciences by investigating the role of electric fields and the local molecular...