This $1.2 million National Science Foundation project grant, awarded under the Biological Sciences program (CFDA 47.074), will fund research at the University of North Carolina at Chapel Hill from March 2023 through February 2027 toward developing a revised model of the cell cycle that captures reversible and irreversible cell cycle arrest. The principal investigator will define the molecular mechanisms governing the transition between reversible quiescence and irreversible senescence, as well as the flexibility of cell cycle progression and regulation, through perturbation experiments, time-lapse imaging, and computational modeling. Additionally, the grant supports two community outreach activities engaging students in microscopy skills and neurodiverse individuals in image analysis to further scientific understanding of the cell cycle.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1.2m | 2/27/23 |