Project Grant 2133261

Award Date 6/15/22
Completion Date 5/31/26
Dollars Obligated $120K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
New York, NY 10012, USA
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The National Science Foundation awarded New York University a $120,000 Project Grant under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop a mathematical model of mitosis. The award period is from June 15, 2022 to May 31, 2026.

Under the award, NYU will build on previous work modeling cell division to create a more realistic simulation of closed mitosis. Researchers will extend their model to include a deformable elastic nuclear envelope integrating the mitotic spindle and chromosomes. They will also seek to identify how nuclear envelope forces and deformation drive successful chromosome segregation. New algorithms and software will be developed to simulate membrane-cytoskeleton interactions, which are challenging to currently model. This work will provide greater understanding of mitosis across life and aid in correcting errors in cell division.

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