This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $331,189 to develop a new, affordable virus detection technology. The project aims to integrate protein engineering and electrochemical biosensors to create a portable, room-temperature stable platform for virus detection in resource-limited environments. Key components include engineered enzymes for isothermal nucleic acid amplification and an...
The National Science Foundation (NSF), under its Engineering program (CFDA 47.041), awarded a $429,832 Project Grant to the University of Massachusetts (UMass) to develop a novel method for rapid and sensitive detection of nucleic acids such as DNA and RNA. The main objectives of the 5-year project are to: Determine the nanomechanoelectrical transduction principle of nucleic-acid nanostructures tethered to a graphene transistor and oscillating in an electric field. Achieve rapid,...
This National Science Foundation (NSF) CAREER program Project Grant award for $242,687 supports the development of an ultrasensitive nanopore biosensor technology for point-of-care detection and quantification of multiple infectious disease biomarkers. The award, under NSF's Engineering program (CFDA 47.041), aims to create a next-generation nanopore sensing platform that can achieve sub-femtomolar detection limits, enabling rapid and accurate diagnosis of infectious diseases at the point of...
This $402,222 National Science Foundation Project Grant, funded through the Engineering program (CFDA 47.041), supports the development of a new class of simple, inexpensive, portable, and rapid molecular diagnostic platforms. The awardee, University of Cincinnati, will engineer an instrument that can reliably and quickly detect infectious diseases in human samples using a combination of biochemistry, magnetism, fluid physics, and machine learning insights. Specifically, the university will...
This National Science Foundation Project Grant of $180,493 will support the development of an ultrasensitive point-of-care diagnostic system using clustered regularly interspaced short palindromic repeats (CRISPR) technology for early disease detection without pre-amplification of viral genomes. Funded under the NSF's Office of Integrative Activities program (CFDA 47.083), which enhances STEM competitiveness through capacity building and broadening participation, this 24-month project will...
The National Science Foundation (NSF) Directorate for Engineering awarded a $1,999,999 Project Grant under the CFDA 47.041 Engineering program to Virginia Polytechnic Institute & State University (Virginia Tech) on October 15, 2023. The objective of this 4-year project is to develop a biosensing platform that uses engineered living materials to continuously monitor for the presence of various airborne pathogens, including those that could be used as bioterrorism agents. The technology,...
This $447,747 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) to Trustees of Boston University will develop a novel plasmonic nanosensor system to detect two important classes of RNA molecules - microRNA (miRNA) biomarkers and SARS-CoV-2 viral RNA. The sensor platform uses DNA structures with nanoparticle probes that undergo conformational changes when binding to target RNAs, altering the plasmonic coupling signal which is detected via two-color...
The National Science Foundation awarded a $230,000 Project Grant to the Regents of the University of Minnesota under the Engineering federal grant program (CFDA 47.041) to develop a biosensing platform for rapid sorting, trapping, and analysis of extracellular vesicles and viral specimens. Over a three-year period ending in August 2025, the University will combine graphene electrodes and photonic waveguides to create a "waveguide-integrated graphene nano-tweezers" platform. This...
The National Science Foundation awarded a $250,000 Project Grant to the University of Pittsburgh under the Engineering federal grant program (CFDA 47.041) to develop a biosensor platform for rapidly sorting and analyzing nanoscale vesicles and viruses. The three-year award will support the design and demonstration of a waveguide-integrated graphene nano-tweezers platform that combines transparent dielectrophoretic graphene electrodes and silicon nitride photonic waveguides. By integrating...
The National Science Foundation awarded a $294,100 project grant to the University of Kansas Medical Center Research Institute, Inc. to support research titled "EAGER: ENGINEERING OPTICAL NANOBIOSENSORS FOR DETECTION OF CORONAVIRUS PROTEASES" under the NSF Engineering program (CFDA 47.041). The grant funding will support the development of optical nanobiosensors for detecting coronavirus proteases from March 15, 2021 through October 31, 2022. The NSF Directorate for Engineering seeks...