The National Science Foundation (NSF), under its Engineering program (CFDA 47.041), awarded a $429,832 Project Grant to the University of Massachusetts (UMass) to develop a novel method for rapid and sensitive detection of nucleic acids such as DNA and RNA. The main objectives of the 5-year project are to:
Determine the nanomechanoelectrical transduction principle of nucleic-acid nanostructures tethered to a graphene transistor and oscillating in an electric field.
Achieve rapid,...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...
The National Science Foundation awarded the University of Illinois a $100,000 project grant under the NSF Technology, Innovation, and Partnerships program to develop an aerial virus detector system. The university will use the one-year award ending June 2023 to create a portable device that can directly detect airborne COVID-19 and other viral particles. The proposed technology integrates a COVID-reactive surface with a sensitive detection mechanism to identify the presence of a virus...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
This National Science Foundation (NSF) Partnerships for Innovation - Research Partnerships (PFI-RP) project grant, CFDA #47.084, provides $549,649 to the University of Rochester to advance the development of a novel membrane-based sensor technology for the rapid and specific detection of infectious pathogens in biofluids. The project aims to integrate the membrane sensor into a hand-operated microfluidic device with a colorimetric readout, and demonstrate the generalizability of the approach...
This National Science Foundation (NSF) CAREER grant, under the Engineering program (CFDA 47.041), provides $242,687 to the University of Massachusetts for the development of an ultrasensitive nanopore biosensor technology for point-of-care detection of infectious disease biomarkers. The project aims to enable rapid, accurate, and low-cost quantification of multiple biomarkers from human blood samples, addressing the limitations of current point-of-care testing technologies. Key objectives...
This $402,222 National Science Foundation Project Grant, funded through the Engineering program (CFDA 47.041), supports the development of a new class of simple, inexpensive, portable, and rapid molecular diagnostic platforms. The awardee, University of Cincinnati, will engineer an instrument that can reliably and quickly detect infectious diseases in human samples using a combination of biochemistry, magnetism, fluid physics, and machine learning insights. Specifically, the university will...
This National Science Foundation Project Grant of $180,493 will support the development of an ultrasensitive point-of-care diagnostic system using clustered regularly interspaced short palindromic repeats (CRISPR) technology for early disease detection without pre-amplification of viral genomes. Funded under the NSF's Office of Integrative Activities program (CFDA 47.083), which enhances STEM competitiveness through capacity building and broadening participation, this 24-month project will...
The National Science Foundation awarded a $294,100 project grant to the University of Kansas Medical Center Research Institute, Inc. to support research titled "EAGER: ENGINEERING OPTICAL NANOBIOSENSORS FOR DETECTION OF CORONAVIRUS PROTEASES" under the NSF Engineering program (CFDA 47.041).
The grant funding will support the development of optical nanobiosensors for detecting coronavirus proteases from March 15, 2021 through October 31, 2022. The NSF Directorate for Engineering...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 supports the development of an automated, AI-supported platform for rapid detection of food pathogens. The key products/services to be delivered include:
Building an automated sample preparation module to enhance pathogen enrichment across food groups.
Developing an automated experimental design workflow to accelerate the optimization of enrichment time.
Using...