Project Grant 2132195
Award Date
2/1/22
Completion Date
1/31/24
Dollars Obligated
$180K
Federal Agency
Office of Integrative Activities
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Farmington, CT 06032, USA
Similar Awards
This $430,785 National Science Foundation (NSF) CAREER award to the Regents of the University of California at Riverside (UC Riverside), awarded under the NSF Engineering program (CFDA 47.041), is focused on developing novel CRISPR-based biosensing technologies for the ultra-accurate detection of disease-related single nucleotide polymorphisms (SNPs). The central goals of the 5-year project are to: 1) enable ultra-accurate SNP detection using a CRISPR-Cas14 biosensor, 2) design a ratiometric SNP...
The National Science Foundation awarded a $199,999 Project Grant under the Engineering (CFDA 47.041) program to The Trustees of the University of Pennsylvania to develop a next-generation RNA detection tool for infectious disease diagnosis. The project aims to engineer a thermostable version of the CRISPR-Cas13 enzyme to improve its stability and sensitivity for field applications. By combining the enhanced Cas13 enzyme with advanced electrochemical devices, the researchers will create an...
This National Science Foundation Project Grant, funded under the Engineering program (CFDA 47.041), aims to improve the stability and sensitivity of a heat-resistant version of the CRISPR-Cas13 enzyme for accurate and robust detection of disease-causing RNA. The $200,000 award, effective November 1, 2024 through October 31, 2027, supports the University of Connecticut's efforts to engineer the Cas13 enzyme for enhanced thermostability, protease resistance, and target sensitivity. The...
This $199,997 federal Project Grant, awarded by the National Science Foundation's Engineering program (CFDA 47.041), aims to improve the stability and sensitivity of a heat-resistant version of the CRISPR-Cas13 enzyme for rapid and accurate detection of disease-causing RNA. The collaborative research project between William Marsh Rice University and its partners will leverage mechanism-based protein engineering and electrochemical devices to generate next-generation RNA detection tools for...
This $495,516 Project Grant, awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), aims to develop a next-generation, ultrasensitive, and easy-to-use diagnostic platform for detecting nucleic acids as biological markers for diseases and pathogens. The key innovations focus on: (1) signal amplification through redox-tagged reporter aptamers in a graphene microstructure array; (2) enhancing charge transfer kinetics through plasma-induced graphene...
The National Science Foundation (NSF), under its Engineering program (CFDA 47.041), awarded a $429,832 Project Grant to the University of Massachusetts (UMass) to develop a novel method for rapid and sensitive detection of nucleic acids such as DNA and RNA. The main objectives of the 5-year project are to: Determine the nanomechanoelectrical transduction principle of nucleic-acid nanostructures tethered to a graphene transistor and oscillating in an electric field. Achieve rapid,...
This Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $331,189 to develop a new, affordable technology for virus detection. The project integrates protein engineering and electrochemical biosensors to create a portable, room-temperature stable platform for virus testing in resource-limited environments. Key innovations include the use of stable enzymes that can be stored at ambient temperatures,...
This $960,000 National Science Foundation project grant supports the development of a multiplexed plasmon-enhanced lateral flow assay for point-of-care detection of SARS-CoV-2 RNA and antigens. Funded under the NSF Engineering program (CFDA 47.041), the grantee, Washington University, will design, validate and build a novel diagnostic platform with sensitivity exceeding standard laboratory tests. Key deliverables include an ultrasensitive multiplexed lateral flow assay for simultaneous...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...
This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...