Project Grant 2140320
- This Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences provides $1,068,886 to Michigan State University under the Biological Sciences program (CFDA 47.074) from December 15, 2022 through November 30, 2025. The grant supports research examining the effects of shear flow on transient biomolecular interactions and aggregation in dense biological environments through integrated experimental and computational approaches. Michigan State University will...
- The National Science Foundation awarded a $200,000 Project Grant to the University of Michigan for research activities under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The three-year award, issued on October 1, 2021 and concluding on September 30, 2024, will support the University's collaborative research project titled "CIF: MEDIUM: GROUP TESTING FOR REAL-TIME POLYMERASE CHAIN REACTIONS: FROM PRIMER SELECTION TO AMPLIFICATION CURVE...
- The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the Regents of the University of Michigan under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new high-throughput technologies for characterizing the 3-dimensional structures of proteins and RNA. Specifically, the funding will support Professor Brandon Ruotolo and his research team in expanding the capabilities of Collision Induced Unfolding (CIU) - an approach that uses...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $750,000 Project Grant titled "TRANSITIONS: EVOLVING OUR UNDERSTANDING OF DYNAMIC RNA FOLDING AND FUNCTION" to Northwestern University under the Biological Sciences grant program (CFDA 47.074). The objective of this 3-year award is to uncover fundamental principles linking RNA sequence to dynamic RNA folding processes and function in biological systems. The research aims to enhance the...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $1,000,000 to the University of Michigan provides funding from August 1, 2024 to July 31, 2028 to study the molecular mechanism of telomere maintenance in the model organism Caenorhabditis elegans. The research aims to leverage the simplicity of the worm's shelterin protein complex to answer fundamental questions about the structure and function of these proteins in chromosome end protection and...
- This National Science Foundation Project Grant award of $299,998 provides funding from July 1, 2022 through June 30, 2024 to develop magnetothermal control of cell fates and function. The award is made under the NSF Engineering program (CFDA 47.041) to Michigan State University. Specifically, the funding supports research to engineer prokaryotic cells as programmable pseudo-organelles that can be controlled using alternating magnetic fields to activate mammalian transcription factors and...
- The National Science Foundation awarded a $207,000 Project Grant to support research titled "Influence of M6A in Gene Regulation and Protein Occupancy in Bacillus subtilis" from March 2021 through February 2024. The grant was awarded under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and understanding of major problems. The grant will fund...
- This $750,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports the development of a novel platform to enable rapid and robust identification of functional RNA molecules directly within mammalian cellular environments. The research aims to solve the challenge of RNA structure sensitivity to local environments that has hindered progress in the field of functional RNA discovery. The project will deliver a customized...
- The University of Michigan was awarded a two-year, $349,312 Project Grant from the National Science Foundation under the Biological Sciences federal grant program (CFDA 47.074). The grant aims to enhance capabilities for forecasting tree species population trajectories under changing environments through synthesis. Specifically, the University will conduct research to increase scientific understanding of major problems confronting the nation by promoting progress in the biological sciences....
- This Project Grant, awarded by the National Science Foundation's Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), provides $583,025 to Professors Shiyue Fang and Yinan Yuan of Michigan Technological University to develop new chemical technologies for the synthesis of long oligonucleotides (DNA and RNA segments). The research aims to overcome limitations of current biological methods and enable cost-effective production of long oligonucleotides essential for applications in...
The University of Michigan will receive $675,000 under a three-year Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences. The grant funds research titled "Unveiling Functionally Critical, Ephemeral RNA (Un)folding States with Magnetic Tape Head Tweezers" from December 2021 through November 2024. The research aims to advance understanding of major problems in biological sciences by using magnetic tweezers to study transient unfolding states of RNA molecules. This work aligns with the Biological Sciences program administered by NSF, which supports basic research to strengthen the nation's scientific enterprise and increase knowledge of challenges in the field. The grant enables investigation of functionally important unfolding dynamics that are difficult to observe using other methods, with results expected to provide new insights into RNA structure and function.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $675.0k | 11/8/21 |