Project Grant 2200991
- This Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to advance the scientific understanding of magnetogenetics, a groundbreaking biological technology that uses magnetic fields and nanoparticles for noninvasive control of cell activities. The $205,994 award, provided to the University of Kentucky Research Foundation, will integrate novel computational modeling and experimental methods to thoroughly analyze the nanoscale energy conversion...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) funds the "Collaborative Research: DMREF: Adaptive and Responsive Magnetic Swarms (ARMS)" project. The $499,998 grant supports research to build and steer cooperative swarms of micron-scale magnetic particles that can propel through fluids, maneuver over surfaces, and respond to their surroundings - similar to schools of fish or flocks of birds. This effort aims to advance the field of...
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will develop a sub-millimeter scale "Gel-Bot" robot inspired by the sensing and movement capabilities of amoebas. The $296,412 award to Michigan State University, spanning September 2025 to August 2028, will create this soft composite hydrogel microrobot with integrated neuromorphic control systems. The Gel-Bot will have applications in minimally invasive medical diagnostics and...
- The University of Michigan will receive $675,000 under a three-year Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences. The grant funds research titled "Unveiling Functionally Critical, Ephemeral RNA (Un)folding States with Magnetic Tape Head Tweezers" from December 2021 through November 2024. The research aims to advance understanding of major problems in biological sciences by using magnetic tweezers to study transient unfolding states...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $199,927 to Montana Technological University to research and develop a new class of shape-changing "mechanical metamaterials" that can morph in response to alternating magnetic fields. The research aims to harness chaotic dynamics and multistability to enable energy-efficient shape transformation in soft magnetic spherical metamaterials. Unlike existing shape-morphing...
- This $325,937 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports collaborative research at Michigan State University (MSU) to interrogate the interconnection of structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments. The project aims to study the impact of geometry and permeability of microcompartments in two distantly related bacteria under varying realistic environments, with the goal of gaining...
- This $244,955 Project Grant awarded by the National Science Foundation (NSF), under the Mathematical and Physical Sciences program (CFDA 47.049), supports theoretical and computational research to develop advanced computational tools and use them for describing the dynamical behavior of magnetic molecules connected to external electrodes and manipulated by magnetic fields. The research aims to provide a balance between computational efficiency and physical accuracy in simulating such open...
- This federal Project Grant award of $787,016 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the Florida Institute of Technology (Florida TECH) to investigate the role of quantum processes in regulating reactive oxygen species (ROS) production in living cells. The project aims to observe and analyze how quantum-level phenomena involving electron spin and radical pair formation can influence cellular metabolism, signaling, and stress...
- The $120,000 National Science Foundation Project Grant, funded through the Engineering program (CFDA 47.041), supports research at the University of Maryland, College Park to engineer atomically thin magnetic materials for solid-state cryogenic cooling below 1 Kelvin. Over the one-year period from January 2023 to December 2023, the university researchers will apply first-principles simulations to understand magnetism-structure relationships in two-dimensional magnets. They will also employ...
This National Science Foundation Project Grant award of $299,998 provides funding from July 1, 2022 through June 30, 2024 to develop magnetothermal control of cell fates and function. The award is made under the NSF Engineering program (CFDA 47.041) to Michigan State University. Specifically, the funding supports research to engineer prokaryotic cells as programmable pseudo-organelles that can be controlled using alternating magnetic fields to activate mammalian transcription factors and direct host gene expression. The researchers will develop genetically engineered magnetoendosymbionts using magnetotactic bacteria coated in iron particles. The goal is to program these engineered organelles to express transcription factors targeted to host cell nuclei for reprogramming differentiated macrophages into induced pluripotent stem cells and then into hepatocytes. Once demonstrated in vitro, the transcription factor operons will be transferred to the magnetotactic bacteria for magnetothermal control of cellular reprogramming and differentiation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $150.0k | 6/28/22 |