Project Grant 2431589

Award Date 9/1/24
Completion Date 8/31/26
Dollars Obligated $400K
Federal Grant Program
47.070
Assistance Type
Project Grant
Place of Performance
Long Beach, CA 90840, USA
Similar Awards
This National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) award of $1,200,000 provides funding to the University of California, Berkeley from October 1, 2024 to September 30, 2028 to develop innovative sensing technologies that integrate DNA nanotechnology and CMOS electronics for next-generation diagnostics. The key objectives of this project grant are to: (1) develop molecular engineering techniques using DNA origami...
This $435,054 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research and development of a solid-state nanopore-based point-of-care nucleic acid testing device. The award aims to address key challenges in translating solid-state nanopore sensors to practical settings, including reproducible size control, introducing specificity, prolonged sensing time at low analyte concentrations, and integrated sample preparation. The research...
This National Science Foundation (NSF) Project Grant award for $380,074, awarded on September 1, 2024, aims to develop a platform for instrument-free, easy-to-interpret quantitative analysis of molecular biomarkers. The project will produce a general methodology adaptable to a range of molecular targets, including potential new agents. The key products to be delivered include: A "yes/no" output for quantitative measurement, enabled through stoichiometry and negative cooperativity-based...
This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) is focused on developing a new, affordable technology to test for viruses with high accuracy. The $331,189 project, awarded on April 1, 2025, employs protein engineering to create stable enzymes that can be stored at room temperature and used with electrochemical biosensors and microfluidics technology to create a portable, cost-effective virus detection...
This National Science Foundation Project Grant of $180,493 will support the development of an ultrasensitive point-of-care diagnostic system using clustered regularly interspaced short palindromic repeats (CRISPR) technology for early disease detection without pre-amplification of viral genomes. Funded under the NSF's Office of Integrative Activities program (CFDA 47.083), which enhances STEM competitiveness through capacity building and broadening participation, this 24-month project will...
This $432,740 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the Cal Poly Corporation supports the development of a new class of paper-based chronometric biosensors. The objective is to create quantitative point-of-care diagnostic tools that can detect a range of biological analytes, including disease markers, environmental contaminants, and security threats, using time as the sensing signal. The novel biosensors will leverage polymer...
This National Science Foundation (NSF) Project Grant under the Engineering program (CFDA 47.041) will develop automated lab-on-a-chip platforms to enable comprehensive monitoring and control of live cell physiology. The $406,165 award to George Washington University, starting on September 1, 2024, will fund research to create innovative materials, devices, circuits, software, and integrated systems for real-time, multiparametric analysis of live cell models like induced pluripotent stem...
This $448,818 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) aims to develop a miniaturized, sensitive, and user-friendly electromagnetic (EM) biosensing platform to rapidly detect and identify bacterial infections. The project combines physics-based dielectric spectroscopy and biochemistry-based magnetic nanoparticle detection to capture unique signatures of various bacterial strains. Key innovations include: 1) ultrasensitive biosensing...
This National Science Foundation (NSF) CAREER grant award under the Engineering program (CFDA 47.041) provides $242,687 to the University of Massachusetts to develop an ultrasensitive nanopore biosensor technology for point-of-care detection of infectious disease biomarkers. The key objectives are to: (1) optimize a highly sensitive and robust nanopore sensor, (2) enable specific biomarker detection using automated immunoprecipitation and novel signal transduction, and (3) demonstrate...
This $402,222 National Science Foundation Project Grant, funded through the Engineering program (CFDA 47.041), supports the development of a new class of simple, inexpensive, portable, and rapid molecular diagnostic platforms. The awardee, University of Cincinnati, will engineer an instrument that can reliably and quickly detect infectious diseases in human samples using a combination of biochemistry, magnetism, fluid physics, and machine learning insights. Specifically, the university will...

This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include:

  1. Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and performance.
  2. Miniaturizing actuation, sensors, and readout systems using CMOS technology for seamless bio-sample characterization without optical components.
  3. Defining design rules for implementing label-free cell characterization and dielectrophoresis-impedance protein detection methods using 3D-printed electrodes.
  4. Leveraging artificial intelligence to optimize the fabrication process of the 3D-printed conductive electrodes.

This project aims to address global healthcare challenges and disparities by enhancing the accessibility and affordability of advanced biomedical diagnostic technologies, particularly in resource-limited environments. The award is held by the California State University Long Beach Research Foundation, a minority-serving, non-profit research institution, and will be executed over a 2-year period from September 2024 to August 2026.

Generated 5/13/25, 4:11 AM