Project Grant 2100563
- This Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences CFDA program (47.074), will investigate a novel regulatory mechanism called "RNA buffering" that maintains messenger RNA (mRNA) levels despite changes in synthesis and decay rates. The $749,978 project at the University of Utah will explore the protein-protein and protein-RNA interactions involved in this process, which challenges...
- The National Science Foundation (NSF) awarded a $1,199,997 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Colorado-Denver. The grant will fund research to improve understanding of the mechanisms underlying messenger RNA (mRNA) localization and translation, and develop machine learning models to better predict protein production from mRNA. The project will apply recent advancements in RNA sequencing technology to study how factors like tRNA abundance and...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $949,953 Project Grant to the Research Foundation Of The City University Of New York, doing business as Rfcuny - Hunter College, from August 1, 2023 to July 31, 2026. The grant, funded under the Biological Sciences program (CFDA 47.074), will support research to identify molecular interactions and build a detailed model of translational regulation, specifically examining the role of eIF3 and 4E-BP in...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences program (CFDA 47.074) provides $522,131.00 to New York University (NYU) from August 1, 2023 to July 31, 2026. The funded research aims to understand the relationship between RNA sequence features and splicing outcomes, as well as the role that nuclear speckles play in RNA splicing decisions. The project will leverage high-throughput assays and interpretable machine learning to identify sequence-encoded...
- The University of Utah will receive $492,516 from the National Science Foundation Division of Molecular and Cellular Biosciences under a three-year Project Grant award titled "Role of Electric Fields and a Dynamic Local Environment in Protein-RNA Molecular Recognition." The grant funds basic research from August 1, 2021 to July 31, 2024 to advance understanding of major problems in the biological sciences by investigating the role of electric fields and the local molecular...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $1,050,000 Project Grant to Princeton University to deepen the understanding of chemical modifications on ribonucleic acid (RNA) and their role in biological processes. The 3-year project, titled "Illuminating the Dihydrouridine Epitranscriptome," aims to characterize the RNA modification dihydrouridine (D) and its writer enzymes, as well as elucidate their biological function...
- This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $950,000 to The Research Foundation For The State University Of New York from February 2023 through January 2026. The award supports research into regulating iron homeostasis by controlling the fate of intracellular ferritin. A multidisciplinary team will use structural biology, spectroscopy, microscopy, proteomics, and other analytical tools to delineate the mechanisms determining...
- This $300,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences will support research into the structural biology of RNA and RNA-protein interactions through May 2024. Funded under the Biological Sciences program (CFDA 47.074), this award to Vanderbilt University will utilize joint cryo neutron/x-ray crystallography techniques to better understand the importance of the 2'-hydroxyl group in RNA's expanded three-dimensional structure compared to DNA....
- This $445,000 federal project grant was awarded on January 23, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports research conducted by the Beckman Research Institute of the City of Hope, a nonprofit medical research organization in California, to elucidate the molecular mechanisms by which protein arginine methylation regulates gene expression, RNA metabolism, and human biology and...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training Program provides $144,362.00 to The Research Foundation For The State University Of New York to investigate the mechanism of Ess1-mediated regulation of the CTD of RNAP II phase separation. The project will be conducted at the Upstate Medical Center in Syracuse, NY and is expected to be completed by April 30, 2025. This research aims to...
The National Science Foundation awarded a $1,109,203 Project Grant to The Research Foundation For The State University Of New York to elucidate the role of protein arginine methylation in regulating RNA-binding protein function from May 2021 through April 2025. This award supports research under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the Nation's scientific enterprise through increasing scientific knowledge and enhancing understanding of major problems confronting the Nation. Specifically, this four-year Project Grant will fund research investigating how post-translational modifications of arginine residues impact RNA-binding protein function and regulation. Insights gained from this work could further biological understanding and potentially address national priorities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 5/21/21 | ||
| Not listed | $1.1m | 4/15/21 |