This National Science Foundation (NSF) Project Grant award under the Biological Sciences program (CFDA 47.074) provides $522,131.00 to New York University (NYU) from August 1, 2023 to July 31, 2026. The funded research aims to understand the relationship between RNA sequence features and splicing outcomes, as well as the role that nuclear speckles play in RNA splicing decisions. The project will leverage high-throughput assays and interpretable machine learning to identify sequence-encoded mechanisms that contribute to splicing outcomes. It will also characterize how RNA substrates, spliceosomal components, and splicing factors are positioned relative to nuclear speckles. The research is expected to reveal novel insights into the sequence logic of RNA splicing and the function of nuclear speckles in this process. The award further supports the development and dissemination of an interdisciplinary curriculum, as well as efforts to recruit, involve, and provide career development opportunities for students and scholars from diverse backgrounds in biological and computational research and education.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $522.1k | 7/12/23 |