This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $950,000 to The Research Foundation For The State University Of New York from February 2023 through January 2026. The award supports research into regulating iron homeostasis by controlling the fate of intracellular ferritin. A multidisciplinary team will use structural biology, spectroscopy, microscopy, proteomics, and other analytical tools to delineate the mechanisms determining ferritin trafficking within and out of cells. They will explore previously uncharacterized interactions between NCOA4, PCBP1, and ferritin at the biochemical, biophysical, and structural levels. A $950,000 subaward to Dana-Farber Cancer Institute will support related research. The funding promotes progress in the biological sciences and scientific understanding of major problems by supporting basic research, with the goals of this award being to elucidate molecular mechanisms of cellular and systemic iron homeostasis.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $950.0k | 2/9/23 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
250118118896925S | Dana-Farber Cancer Institute, Inc. | Project Grant 2231900 | $384.9k | 5/1/23 |