Project Grant NNX15AB44G

The University of California, San Diego will receive $400,000 from the National Science Foundation under the Engineering (CFDA 47.041) federal grant program to research the mechanisms of microgravity accelerated aging on human brain organoids from October 1, 2021 to September 30, 2024. Through this three-year Project Grant, UCSD researchers will study how microgravity exposure impacts the aging process in miniaturized human brain tissues grown in a laboratory, with the goal of furthering...

This $100,000 Cooperative Agreement award from the National Aeronautics and Space Administration (NASA) Office of STEM Engagement (OSTEM) program (CFDA 43.008) supports research to develop guidelines for prescribing appropriate flywheel-based inertial training (FIT) workloads for exercise in spaceflight. The University of Kentucky Research Foundation, a non-profit research organization, is the prime awardee and will execute the project from September 1, 2024 through August 31, 2025. The research...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $399,146 Project Grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to develop a bioreactor system for conducting research on the effects of microgravity and aging on neuromuscular function. The objectives are to evaluate force generation and reactive oxygen species production in tissue-engineered human nerve-muscle constructs,...

This $449,582 National Science Foundation project grant funds research at Virginia Polytechnic Institute and State University from October 1, 2022 to September 30, 2025 under the NSF Engineering program (CFDA 47.041). The research aims to understand the effects of microgravity on wound healing processes by leveraging a sensor-integrated 3D tissue culture model. Specifically, the project will explore dynamic changes in gene and protein expression, structural changes in capillary network formation...

Trans Astronautica Corporation received a $124,891 Project Grant award from the National Aeronautics and Space Administration (NASA) Shared Services Center under the NASA Space Technology Mission Directorate's Space Technology program. The grant will support Trans Astronautica Corporation's efforts to develop large space habitats with robust agricultural systems and ample green space from April 1, 2021 to December 15, 2021. NASA's Space Technology program aims to transform future space...

This National Science Foundation Project Grant of $400,000 supports research at the University of Alabama at Birmingham from January 2023 through December 2025 under the Engineering program (CFDA 47.041). The award will leverage the space environment to study the molecular mechanisms by which the bacterium Streptococcus pneumoniae causes cardiac toxicity and infection. Researchers will use a cardiac tissue chip model on the International Space Station to identify critical factors that allow S....

This $400,000 National Science Foundation project grant supports research at Tufts University aimed at understanding the impact of aging on wound healing processes. Specifically, the grant funds two years of research to determine the effects of microgravity on fibroblast phenotype and wound healing response across tissue types and developmental ages. Investigators will leverage the unique environment of the International Space Station to simulate aging processes and their influence on tissue...

The National Aeronautics and Space Administration (NASA) awarded a $329,405 Project Grant under the Science Mission Directorate (CFDA 43.001 - Science) to the University of North Dakota (UND) for a 3-year project titled "Devising Defenses: Curtailing Microbial Risks (CMR) in a Closed Human Habitat and Spacesuit Fabrics." The project aims to conduct research and develop solutions to mitigate microbial risks in closed human habitats and spacesuit materials for NASA's space exploration...

This $382,124 federal Project Grant award, made by the National Science Foundation's Engineering program (CFDA 47.041), aims to advance tissue engineering and in-space cell technologies for regenerative medicine applications. The award will fund a collaborative effort between Micro-Grx, Inc., the University of Florida, Ronawk, and Redwire to develop three-dimensional "bio-block" tissue models that mimic the vascularization of heart and skin cells. These bio-block organoids will be used...

The Trustees of Princeton University, Office of Research and Project Administration, received a $340,033 project grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the NSF Engineering directorate program (CFDA 47.041). The project, titled "ISS: The Influence of Microgravity on Bacterial Transport and Pellicle Morphogenesis," investigates the formation and growth of pellicles - bacterial communities that...