Cooperative Agreement W81XWH1720049

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $349,734 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Actiox LLC, a biomedical technology company in Thousand Oaks, California. The project aims to develop a wearable microneedle-based biosensor for continuous, real-time cardiac troponin I monitoring. The goal is to demonstrate the feasibility of this transformative biosensor technology to enable earlier detection of ischemic events and...

Dynocardia Inc. received a $256,000 National Science Foundation Project Grant to advance development of a novel continuous, cuffless blood pressure monitoring device. Funded through the NSF Engineering Directorate's SBIR program, the award will support Dynocardia's efforts to address motion artifacts and enable accurate, beat-to-beat blood pressure measurements in hospital intensive care and operating room settings. Accurate 24-hour blood pressure monitoring has potential to significantly...

This federal Project Grant award of $134,537 from the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a novel, noninvasive and auto-calibrated pulse-oximetry method that can more accurately and unbiasedly determine a person's arterial oxygen saturation compared to conventional pulse-oximetry. The key products and services to be delivered through this 5-year project include: 1) Theoretical development of the...

This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $237,827 to Brigham & Women's Hospital Inc. to develop a wearable, non-invasive optical device for continuous blood pressure monitoring in neonates. The device, called CNAP-FlexNIRS, will use near-infrared spectroscopy and photoplethysmography to collect high-resolution pulsatile waveforms and...

Sentire Medical Systems, Inc. was awarded a $256,000 National Science Foundation Project Grant to develop an intraoperative monitoring device to detect bowel injuries during laparoscopic surgical procedures. The goal of the NSF Technology, Innovation, and Partnerships program is to advance science and engineering research leading to breakthrough technologies that address national challenges. Through this award, Sentire Medical will characterize gases present during laparoscopic surgery to...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is focused on developing a next-generation photoacoustic computed tomography device for non-invasive monitoring of brain oxygen metabolism. The $249,000 award, spanning July 2025 to June 2028, aims to design, fabricate, and validate a handheld photoacoustic imaging device that...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $374,378 to Michigan State University to develop a computational modeling framework for a miniaturized, noninvasive, wireless, luminescence-based carbon dioxide sensing wearable device. The goal is to accurately translate transcutaneous partial pressure of CO2...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding the development of an innovative portable device to rapidly detect and monitor traumatic brain injury (TBI) biomarkers. The $332,122 award to Hemex Health Inc. aims to create a point-of-care diagnostic platform that can quickly analyze whole blood samples to identify elevated...

This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $318,724 to Pendar Technologies LLC to develop and test an optical probe for monitoring peripheral tissue oxygenation in critically ill neonates. The award will fund improvements to the company's resonance Raman spectroscopy-based sensor technology, which can measure tissue oxygen saturation...

The federal Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research Program (CFDA 93.394) provided $1,164,814 to O2M Technologies LLC to develop an advanced imaging system using pulse electron paramagnetic resonance (PEPR) techniques. The goal is to create a fast and precise method for measuring partial oxygen pressure (pO2) in tissues, which can guide cancer treatment and other medical applications. The project involves establishing the hardware for...