The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,683,996 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to The Regents of the University of Colorado (CU) to develop a novel 3D dynamic contrast optical coherence microscopy (3D DYC-OCM) imaging technology. The project aims to simultaneously overcome the voxel rate and axial resolution limitations of existing OCM architectures in order to...
The federal Project Grant award of $249,000 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) supports the development of a high-throughput photoacoustic histology platform for intraoperative pathological diagnosis. The project aims to create an ultrafast reflection-mode ultraviolet photoacoustic microscopy (UV-PAM) system using structured...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program, aims to develop quantitative photoacoustic imaging biomarkers for characterizing thrombosis. The $341,598 award will fund research at Oakland University to: 1) characterize the unique optical properties of biological chromophores relevant to thrombus...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $192,168 to The Regents of the University of Colorado to develop a miniaturized micro-optical coherence tomography (MOCT) endoscopic system. The key objectives are to: 1) Demonstrate a low-voltage, high-speed electrowetting prism scanner for spectral-domain...
This $100,000 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) will fund the development of blood-mimicking phantoms for assessing oximetry performance of photoacoustic imaging systems. Specifically, the University of California, San Diego will create specialized plastic objects that mimic human tissue with varying levels of oxygenation. These objects will be used to calibrate and standardize photoacoustic imaging equipment by having...
This $568,151 Project Grant awarded by the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394) aims to develop a real-time photoacoustic imaging platform to accurately detect and characterize the aggressiveness of prostate cancer tumors. The Regents of the University of Michigan, the awardee, will optimize photoacoustic nanoprobes to enable chemical imaging of the tumor microenvironment, target prostate cancer, and assess prostate gland...
This federal Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $550,000 to William Marsh Rice University to develop a novel signal encoding and decoding framework that enables the miniaturization of photoacoustic imaging (PAI) systems. The goal is to create compact, affordable, and energy-efficient wearable medical imaging devices capable of continuously monitoring health in daily life. The technical approach involves implementing a...
This federal Project Grant award, valued at $2,156,000.00 and provided by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), aims to develop innovative neuroimaging methods for quantifying oxygen availability, pH, and carbon dioxide levels in brain tissue. The goal is to establish a transformative approach that can provide new insights into the relationship between neurovascular coupling, metabolic processes, and loss of...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $2,278,167 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to the University of North Carolina at Chapel Hill (UNC-CH) and the California Institute of Technology (Caltech). The grant, effective August 20, 2024 through April 30, 2028, supports the development of non-invasive transcranial volumetric super-resolution...
This $305,000 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is funding the development of a miniature diamond quantum sensor for magnetoencephalography (MEG) imaging. The goal is to create a lower-cost, high-resolution brain imaging system to study neurological disorders like traumatic brain injury, schizophrenia, and epilepsy....
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) provides $249,000.00 to The Regents of the University of Colorado (CU) to develop a next-generation photoacoustic computed tomography device called PACTER. The goal is to create a non-invasive, cost-effective, and highly accessible technology for real-time monitoring of cerebral metabolic rate of oxygen (CMRO2) in neurology and brain health applications. The 3-year project aims to design, fabricate, and validate the PACTER device to enable high-resolution vascular imaging of oxygen metabolism, overcoming limitations of current CMRO2 monitoring methods. This research is expected to advance personalized diagnostics, treatment guidance, and surgical decision-making, ultimately improving medical outcomes and quality of life.