This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $237,827 to Brigham & Women's Hospital Inc. to develop a wearable, non-invasive optical device for continuous blood pressure monitoring in neonates. The device, called CNAP-FlexNIRS, will use near-infrared spectroscopy and photoplethysmography to collect high-resolution pulsatile waveforms and...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
This federal Project Grant award of $371,021 was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) to Makani Science Inc., a small business located in Irvine, California. The goal of this 2-year award (4/9/2025 - 2/28/2027) is to develop an apnea monitoring platform capable of accurately identifying the major types of apnea of prematurity (central, obstructive, and mixed) in premature newborns. The proposed work...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), is funding the development and testing of a novel wearable device to continuously and accurately measure blood loss for postpartum hemorrhage (PPH) prevention. The $639,165 award, spanning May 2025 to February 2030, supports research at Washington University to design a light-based sensor that can estimate cardiovascular parameters and...
The National Institute of Child Health and Human Development (NICHD) awarded a $624,998 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Giner Inc., a small business R&D firm in Auburndale, Massachusetts. The grant will fund the development and validation of an electrochemical assay and point-of-care instrument for rapid, highly sensitive, and specific measurement of oxytocin levels. Oxytocin is a critical neuropeptide hormone involved...
The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
This Project Grant award of $291,523 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to develop an AI-driven Total Parenteral Nutrition (TPN) platform for premature newborns in neonatal intensive care units (NICUs). The key goals are to create standardized TPN units for cost-effective and personalized nutrition, and validate the TPN2.0 platform against the best standard of...
This Project Grant award from the Department of Health and Human Services National Institutes of Health National Institute of Child Health and Human Development provides $769,916 to Emergent Biotechnologies LLC for research into a novel therapy for preeclampsia. The funding supports Phase 1 of developing and characterizing a handle region peptide as an innovative treatment for preeclampsia under the Child Health and Human Development Extramural Research program (CFDA 93.865). Phase 1 work will...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $249,000 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The Regents of the University of Colorado. The grant will fund the development of a next-generation photoacoustic computed tomography through an ergodic relay (PACTER) device for non-invasive monitoring of cerebral metabolic rate of oxygen. The project aims to address the...
This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...