Project Grant R21HD117308

Award Date 12/10/24
Completion Date 11/30/26
Dollars Obligated $238K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Boston, MA 02115, USA
Similar Awards
The federal Project Grant award of $318,724 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the advanced development and testing of an optical probe that monitors peripheral tissue oxygenation as a marker of systemic hemodynamics. The goal is to enable early identification of shock states in critically ill neonates through a non-invasive, precise measurement of tissue...
The National Institute of Child Health and Human Development (NICHD) awarded a 5-year, $747,911 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Women & Infants Hospital of Rhode Island. The grant will fund the implementation and evaluation of RI-SPHERES, a technology-based collaborative care program to improve postpartum hypertension management and preventive care attendance among patients with hypertensive disorders of pregnancy (HDP). The program...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) project grant award provides $347,386 to the University of Illinois to develop a novel wearable device for continuous, cuffless blood pressure (BP) monitoring. The goal is to create an accurate, inexpensive, and easy-to-use technology that can facilitate proactive management of hypertension and reduce hospitalizations related to this condition, which affects 45% of U.S. adults and is a leading risk factor for heart failure....
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $375,750 Project Grant (CFDA 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop and validate a wearable monitor to detect decompensation in cardiac failure patients. The project aims to build a multi-wavelength wearable device capable of non-invasively tracking...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $371,021 to develop an accurate and continuous apnea monitoring platform for premature newborns with apnea of prematurity (AOP). The funding will support the creation of a multimodal sensor system and machine learning algorithms to identify the major AOP types (central, obstructive, and...
The National Institute of Child Health and Human Development (NICHD) awarded Giner Inc., a small business research and development firm, a $624,998 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop a point-of-care testing (POCT) instrument for highly sensitive and near-real-time measurement of oxytocin levels. The project aims to create an electrochemical assay and POCT device that can accurately determine peripheral oxytocin levels...
Dynocardia Inc. received a $256,000 National Science Foundation Project Grant to advance development of a novel continuous, cuffless blood pressure monitoring device. Funded through the NSF Engineering Directorate's SBIR program, the award will support Dynocardia's efforts to address motion artifacts and enable accurate, beat-to-beat blood pressure measurements in hospital intensive care and operating room settings. Accurate 24-hour blood pressure monitoring has potential to significantly...
The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $585,794 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Tele-Stethoscope Inc., a small disadvantaged business, for the development of a novel mobile phone technology to improve access to preeclampsia and hypertension detection. The project aims to demonstrate proof-of-concept that ordinary mobile phones can reproduce physicians' diagnosis of preeclampsia and detect hypertension through advanced...

The National Institute of Child Health and Human Development (NICHD) awarded a Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Brigham & Women's Hospital Inc. in the amount of $237,827 to develop a wearable optical device for continuous non-invasive arterial blood pressure monitoring in neonates. The project aims to create a low-cost, wireless near-infrared spectroscopy (NIRS) device called CNAP-FLEXNIRS that can collect high-resolution NIRS-photoplethysmography (PPG) waveforms to estimate blood pressure in newborns. The hospital will test the device on 20 neonatal intensive care unit (NICU) patients and optimize the NIRS-PPG waveform analysis using deep learning models for improved blood pressure estimation. The ultimate goal is to provide a reliable, non-invasive continuous blood pressure monitoring solution to revolutionize neonatal care and enable real-time data for personalized treatment of infants at risk of blood pressure fluctuations. A sub-award to Massachusetts General Hospital will support device modifications, data collection, and analysis.

Generated 6/24/25, 3:33 AM