Cooperative Agreement UG3DA065155
- This Project Grant award, totaling $1,455,799.00, was provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program. The award is for a research project titled "Miniaturizing Time Resolved Fluorescence Measurements Using Entangled Photons and On-Chip Photonics - Fluorescent Biosensors and Microscopes" at the California Institute of Technology...
- This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $3,044,814.00 to the University of California, Irvine to develop a high-speed, multimodal deep tissue imaging system. The key products and services to be delivered under this 2-year award (9/1/2025 - 8/31/2027) include: Developing a reflection matrix-based wavefront shaping system to overcome light scattering limitations and achieve real-time,...
- The California Institute of Technology (Caltech) was awarded a $315,000 Project Grant from the National Science Foundation (NSF) under the Engineering (47.041) federal grant program. The three-year grant will support Caltech's collaborative research project titled "COLLABORATIVE RESEARCH: FAST SPECTRALLY-ENCODED PHOTOACOUSTIC MICROSCOPY FOR MULTI-PARAMETER BIOENERGETIC CHARACTERIZATION OF HETEROGENEOUS CANCER CELLS." The research aims to develop fast spectrally-encoded photoacoustic...
- The federal Project Grant award of $1,148,652 was made on April 1, 2025 by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The grant supports research and development of an ultra-high spatial resolution photon-counting computed tomography (CT) system with multiple focal spots. The key products to be delivered include: Developing system models and...
- The National Institutes of Health (NIH) awarded a $1,843,229 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to Stanford University, with a project period from September 15, 2025 to August 31, 2027. The project aims to develop a combined Shortwave Infrared (SWIR) Fluorescence and Raman imaging system to enable real-time, high-resolution visualization of tissue structures below the surface. Key objectives include optimizing SWIR Raman imaging to characterize...
- This $769,749 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences will support the development of Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR) technology by Photothermal Spectroscopy Corp. The FE-PTIR technique aims to provide simultaneous fluorescence microscopy and sub-micron infrared spectroscopy to map the distribution of fluorescently labeled biomolecules within cells and tissues while also analyzing their chemical...
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is focused on developing a next-generation photoacoustic computed tomography device for non-invasive monitoring of brain oxygen metabolism. The $249,000 award, spanning July 2025 to June 2028, aims to design, fabricate, and validate a handheld photoacoustic imaging device that...
- This Project Grant award of $616,033 from the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) supports the development and application of a PET-enabled dual-energy CT (DECT) imaging method at the University of California, Davis. The key objectives of this project are to develop a DECT imaging approach that leverages the inherent annihilation-photon attenuation properties of a PET...
- This Cooperative Agreement, awarded by the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) federal grant program (CFDA 93.384), provides $4,116,367 to Northeastern University and its sub-awardees University of Washington, Johns Hopkins University, and Massachusetts General Hospital. The funding supports the development of a "Fully Integrated Acousto-Optical Electronic-Photonic System for Real-Time In Vivo 3D Photoacoustic...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $502,841 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to The Regents of the University of California, operating as Lawrence Berkeley National Laboratory (LBNL). The funding will support research and development of a novel detector readout concept for monolithic scintillation detectors that enables direct digitization...
The U.S. National Institutes of Health (NIH) awarded a $3,179,146 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to the California Institute of Technology (Caltech) to develop next-generation photoacoustic computed tomography (PAT) technology. The project aims to push PAT imaging depth from the current limit of 1 mm to 6 cm while maintaining high spatial resolution. Key technical advancements include optimizing signal-to-noise ratio, enhancing ultrasonic detection, refining joint reconstruction, and mitigating motion artifacts. The 2-year project, starting on September 1, 2025, will culminate in in vivo human breast imaging and validation against contrast-enhanced MRI. Caltech has demonstrated extensive capabilities in federal research and development through previous awards from agencies such as DARPA and NSF across domains like photonics, quantum technologies, and astrophysics.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/10/25 | ||
| Not listed | $3.2m | 8/28/25 |