Cooperative Agreement UG3DA065140
- This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $3,044,814.00 to the University of California, Irvine to develop a high-speed, multimodal deep tissue imaging system. The key products and services to be delivered under this 2-year award (9/1/2025 - 8/31/2027) include: Developing a reflection matrix-based wavefront shaping system to overcome light scattering limitations and achieve real-time,...
- This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $1,732,297 to the University of Arizona to develop a novel non-invasive optical imaging approach for assessing skin lesions at multiple scales. The project aims to address limitations in current imaging techniques by utilizing synthetic waves to enable deeper optical imaging within highly scattering skin tissue. The 2-year project period runs from...
- This $769,749 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences will support the development of Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR) technology by Photothermal Spectroscopy Corp. The FE-PTIR technique aims to provide simultaneous fluorescence microscopy and sub-micron infrared spectroscopy to map the distribution of fluorescently labeled biomolecules within cells and tissues while also analyzing their chemical...
- The U.S. National Institutes of Health (NIH) awarded a $3,179,146 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to the California Institute of Technology (Caltech) to develop next-generation photoacoustic computed tomography (PAT) technology. The project aims to push PAT imaging depth from the current limit of 1 mm to 6 cm while maintaining high spatial resolution. Key technical advancements include optimizing signal-to-noise ratio, enhancing ultrasonic...
- This Project Grant award of $573,470 from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) is supporting the development of a new Atomic Force Microscopy-Infrared Spectroscopic Imaging (AFM-IR) technology dubbed "Resonance Enhance Null-Deflection IR (RENDIR) Spectroscopic Imaging." The goal is to overcome limitations of existing AFM-IR systems to enable label-free, nanoscale chemical imaging of biological materials. The award will fund the...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,131,640 to the University of Southern California (USC) to acquire a new high-end multimodal multiphoton fluorescence microscope system. The purpose of this new microscope is to replace an aging system and bring currently non-existent advanced imaging capabilities to support a large user base across several key research areas at USC, including neuroscience,...
- This Project Grant award of $1,249,099 from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) supports the development of a new class of small, bright, tunable, and biocompatible near-infrared (NIR-II) fluorescent probes for deep tissue molecular imaging. The University of California, Irvine (UC Irvine) will create a palette of DNA-stabilized silver nanoclusters (AgN-DNA) that emit in the NIR-II tissue transparency window (1,000-1,700 nm). These new...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,205,290 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the Massachusetts Eye And Ear Infirmary. The grant supports the development of a fluorescence lifetime-based intraoperative imaging system to enhance visualization and real-time feedback for sarcoma surgeries. The project aims to create new tools that can accurately detect...
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the federal Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $124,562 to the University of Southern California to develop a highly multiplexed Raman imaging platform for studying the immune system's role in Alzheimer's disease. The award will fund the creation of a nanoparticle-based approach capable of simultaneously...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $359,995 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to Clemson University. The funding supports the development and validation of a novel X-ray visualized immunosensor (X-VIS) that can be attached to implanted medical devices to detect and monitor local infection biomarkers. The project aims to fabricate a...
The National Institutes of Health (NIH) awarded a $1,843,229 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to Stanford University, with a project period from September 15, 2025 to August 31, 2027. The project aims to develop a combined Shortwave Infrared (SWIR) Fluorescence and Raman imaging system to enable real-time, high-resolution visualization of tissue structures below the surface. Key objectives include optimizing SWIR Raman imaging to characterize subcutaneous tissue composition, applying the technology to study wound healing, infections, and cancer tumor spread, and creating new fluorescent dyes for deeper SWIR imaging. This advanced optical imaging research seeks to overcome limitations of current techniques and provide innovative tools for biomedical and clinical applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 9/2/25 |