36C25220Q0128-0002003.pdf

TBIL Flex® reagent cartridge

Liquid.

SAFETY DATA SHEET

Product identifier

Product type

Section 1. Identification

TBIL Flex® reagent cartridge

Relevant identified uses of the substance or mixture and uses advised against

DEDM0273

(800) 424-9300 (CHEMTREC) (24/365)

Manufactured/supplied : Siemens Healthcare Diagnostics Inc.

511 Benedict Avenue Tarrytown, NY 10591-5097 USA 1-877-229-3711

Product code : K1167, 10445146

Not applicable.

(2012 OSHA Hazard Communication Standard (29 CFR 1910.1200))

SDS # :

Section 2. Hazards identification

Not classified.Classification of the substance or mixture

Signal word : No signal word.

Hazard statements : No known significant effects or critical hazards.

Precautionary statements

Prevention : Not applicable.

Response : Not applicable.

Storage : Not applicable.

Disposal : Not applicable.

GHS label elements

OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product.

Hazards not otherwise classified

: None known.

Not available.

Not available.

Additional information :

Section 3. Composition/information on ingredients sodium benzoate 3.4773 532-32-1 caffeine 2.2629 58-08-2

Ingredient name CAS number%

There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

Substance/mixture :

Occupational exposure limits, if available, are listed in Section 8.

Mixture

Any concentration shown as a range is to protect confidentiality or is due to batch variation.

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 1/10

Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes.

Get medical attention if symptoms occur.

Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Section 4. First aid measures

Eye contact

Skin contact

Inhalation

Ingestion :

Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.

Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Description of necessary first aid measures

Specific treatments : No specific treatment.

Most important symptoms/effects, acute and delayed

Inhalation : No known significant effects or critical hazards.

No known significant effects or critical hazards.:Ingestion

Skin contact : No known significant effects or critical hazards.

No known significant effects or critical hazards.:Eye contact

Over-exposure signs/symptoms

Skin contact

Ingestion

Inhalation No specific data.

No specific data.

No specific data.

Eye contact : No specific data.

Potential acute health effects

See toxicological information (Section 11)

Indication of immediate medical attention and special treatment needed, if necessary

Section 5. Fire-fighting measures

Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Hazardous thermal decomposition products

Specific hazards arising from the chemical

Decomposition products may include the following materials:

carbon dioxide carbon monoxide nitrogen oxides metal oxide/oxides

In a fire or if heated, a pressure increase will occur and the container may burst.

Extinguishing media

None known.

Suitable extinguishing media

Unsuitable extinguishing media

Special protective actions for fire-fighters

In case of fire, use water spray (fog), foam or dry chemical.

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 2/10

Section 5. Fire-fighting measures Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Special protective equipment for fire-fighters

Section 6. Accidental release measures

Environmental precautions

Personal precautions, protective equipment and emergency procedures

Stop leak if without risk. Move containers from spill area. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see Section 13). Dispose of via a licensed waste disposal contractor. Note: see Section 1 for emergency contact information and Section 13 for waste disposal.

: No action shall be taken involving any personal risk or without suitable training.

Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Put on appropriate personal protective equipment.

Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).

Large spill :

Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Small spill :

Methods and materials for containment and cleaning up

For non-emergency personnel

For emergency responders : If specialized clothing is required to deal with the spillage, take note of any information in Section 8 on suitable and unsuitable materials. See also the information in "For non-emergency personnel".

Section 7. Handling and storage

Advice on general occupational hygiene

Conditions for safe storage, including any incompatibilities

Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Protective measures Put on appropriate personal protective equipment (see Section 8).:

Precautions for safe handling

None.

Section 8. Exposure controls/personal protection

Appropriate engineering controls

: Good general ventilation should be sufficient to control worker exposure to airborne contaminants.

Control parameters

Occupational exposure limits

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 3/10

Section 8. Exposure controls/personal protection

Hand protection

Based on the hazard and potential for exposure, select a respirator that meets the appropriate standard or certification. Respirators must be used according to a respiratory protection program to ensure proper fitting, training, and other important aspects of use.

Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary.

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. If contact is possible, the following protection should be worn, unless the assessment indicates a higher degree of protection: safety glasses with side-shields.

Eye/face protection

Respiratory protection :

Body protection Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Environmental exposure controls

: Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Hygiene measures :

Individual protection measures

Skin protection

Other skin protection : Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Section 9. Physical and chemical properties Physical state

Relative density

Liquid.

Not relevant/applicable due to nature of the product.

Not relevant/applicable due to nature of the product.Odor pH

Not relevant/applicable due to nature of the product.Color

Auto-ignition temperature

Flash point

Not available.

[Product does not sustain combustion.]

Not available.

Not available.

Viscosity Not available.

Partition coefficient: n-octanol/water

Flammability (solid, gas) : Not relevant/applicable due to nature of the product.

Solubility in water : Not relevant/applicable due to nature of the product.

Section 10. Stability and reactivity

Conditions to avoid No specific data.

The product is stable.Chemical stability

No specific data.

Incompatible materials :

Possibility of hazardous reactions

: Under normal conditions of storage and use, hazardous reactions will not occur.

Reactivity : No specific test data related to reactivity available for this product or its ingredients.

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 4/10

Section 10. Stability and reactivity

Hazardous decomposition products

Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Section 11. Toxicological information

Acute toxicity sodium benzoate LD50 Oral Rat 4070 mg/kg -caffeine LD50 Oral Rat 192 mg/kg -

Product/ingredient name Result Species Dose Exposure

Carcinogenicity

Not available.

Mutagenicity

Not available.

Teratogenicity

Not available.

Reproductive toxicity

Not available.

Irritation/Corrosion

Not available.

Sensitization

Not available.

Information on the likely routes of exposure

Inhalation : No known significant effects or critical hazards.

No known significant effects or critical hazards.:Ingestion

Skin contact : No known significant effects or critical hazards.

No known significant effects or critical hazards.:Eye contact

Symptoms related to the physical, chemical and toxicological characteristics

Skin contact

Ingestion

Inhalation No specific data.

No specific data.

No specific data.

Eye contact : No specific data.

Specific target organ toxicity (single exposure)

Specific target organ toxicity (repeated exposure)

Not available.

Not available.

Aspiration hazard

Not available.

Information on toxicological effects

: Not available.

Potential acute health effects

Classification caffeine - 3 -

Product/ingredient name NTPIARCOSHA

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 5/10

Section 11. Toxicological information

Not available.

No known significant effects or critical hazards.General :

No known significant effects or critical hazards.Carcinogenicity :

No known significant effects or critical hazards.Mutagenicity :

No known significant effects or critical hazards.Teratogenicity :

Developmental effects : No known significant effects or critical hazards.

Fertility effects : No known significant effects or critical hazards.

Potential chronic health effects

Delayed and immediate effects and also chronic effects from short and long term exposure

Numerical measures of toxicity

Oral 14264.2 mg/kg

Route ATE value

Acute toxicity estimates

Potential immediate effects

: Not available.

Short term exposure

Potential delayed effects : Not available.

Potential immediate effects

: Not available.

Long term exposure

Potential delayed effects : Not available.

Section 12. Ecological information

LogPow BCF Potential

Bioaccumulative potential

Other adverse effects : No known significant effects or critical hazards.

Product/ingredient name sodium benzoate -2.27 - low caffeine -0.091 - low

Toxicity sodium benzoate Acute LC50 484000 to 558000 µg/l Fresh water

Fish - Pimephales promelas 96 hours caffeine Acute LC50 177.49 mg/l Fresh water Daphnia - Daphnia magna - Neonate

48 hours

Acute LC50 151 mg/l Fresh water Fish - Pimephales promelas 96 hours Chronic NOEC 0.12 mg/l Fresh water Daphnia - Daphnia magna -

Neonate 21 days

Product/ingredient name SpeciesResult Exposure

Persistence and degradability

Soil/water partition coefficient (KOC)

: Not available.

Mobility in soil

Not available.

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 6/10

Section 13. Disposal considerations The generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.

Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way. Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

:Disposal methods

Section 14. Transport information

Not regulated.

DOT Classification

No.

TDG Classification

Not regulated.

No.

ADR/RID

Not regulated.

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

UN number

UN proper shipping name

Transport hazard class(es)

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 7/10

Section 14. Transport information

Not regulated.

IATA

No.

No.

Special precautions for user

Transport in bulk according to Annex II of MARPOL and the IBC Code

Transport within user’s premises: always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

: Not available.

Packing group

Additional information

Environmental hazards

Not regulated.

IMDG

No.

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 8/10

Section 15. Regulatory information U.S. Federal regulations

None of the components are listed.

Clean Water Act (CWA) 311: Hydrochloric acid; sodium nitrite

Massachusetts

Clean Air Act Section 112

(b) Hazardous Air Pollutants (HAPs)

: Listed

Clean Air Act Section 602 Class I Substances

: Not listed

Clean Air Act Section 602 Class II Substances

: Not listed

DEA List I Chemicals (Precursor Chemicals)

: Not listed

DEA List II Chemicals (Essential Chemicals)

: Not listed

New York : None of the components are listed.

New Jersey : None of the components are listed.

Pennsylvania : None of the components are listed.

State regulations

TSCA 5(a)2 final significant new use rules: sodium nitrite

TSCA 8(a) CDR Exempt/Partial exemption: Not determined

United States inventory (TSCA 8b): All components are listed or exempted.

SARA 302/304

SARA 304 RQ : 52754368.9 lbs / 23950483.5 kg

Hydrochloric acid 0.0094779 Yes. 500 - 5000 -

Composition/information on ingredients

Name % EHS (lbs) (lbs)(gallons) (gallons)

SARA 302 TPQ SARA 304 RQ

SARA 311/312

Classification : Not applicable.

sodium benzoate 3.4773 No. No. No. Yes. No.

caffeine 2.2629 No. No. No. Yes. No.

Name % Fire hazard

Sudden release of pressure

Reactive Immediate (acute) health hazard

Delayed (chronic) health hazard

Composition/information on ingredients

International regulations

Chemical Weapons Convention List Schedule I Chemicals

: Not listed

Chemical Weapons Convention List Schedule II Chemicals

: Not listed

Chemical Weapons Convention List Schedule III Chemicals

: Not listed

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 9/10

Section 16. Other information History

Date of issue/Date of revision

Version

Notice to reader

Indicates information that has changed from previously issued version.

Key to abbreviations : ATE = Acute Toxicity Estimate BCF = Bioconcentration Factor GHS = Globally Harmonized System of Classification and Labelling of Chemicals IATA = International Air Transport Association IBC = Intermediate Bulk Container IMDG = International Maritime Dangerous Goods LogPow = logarithm of the octanol/water partition coefficient MARPOL = International Convention for the Prevention of Pollution From Ships, 1973 as modified by the Protocol of 1978. ("Marpol" = marine pollution) UN = United Nations

5/12/2017

1.05

Allergen :

Date of issue/Date of revision : 5/12/2017 Date of previous issue : 1/22/2016 Version : 1.05 10/10