Project Grant W81XWH2211012

Grant Award Summary Vanderbilt University Medical Center received a $262,500 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), with award dates from April 1, 2026, through March 31, 2028. The project, titled "Novel Prediction of Recovery of Consciousness in Acute Traumatic Brain Injury," develops a diagnostic tool to improve prognostic...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the U.S. Department of Health and Human Services, under the Federal Grant Program "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286), aims to develop and assess novel frameworks for accurately predicting functional recovery following moderate-to-severe traumatic brain injury (TBI). The $389,813 award to the University of...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,283,334.00 to the Morehouse School of Medicine (MSM) to develop and validate a progressive mouse model for Traumatic Brain Injury-related Alzheimer's Disease and Related Dementias (TBI-ADRD). The project aims to systematically screen mouse strains and TBI injury types to identify the optimal model for recapitulating key neuropathological, neurobiochemical, and neurocognitive features of human...

This Cooperative Agreement award from the Uniformed Services University of the Health Sciences (CFDA 12.750 - Uniformed Services University Medical Research Projects) provides $1,857,850.00 in funding to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. to support research on a novel anti-inflammatory treatment for traumatic brain injury (TBI). The key objectives of the research project include: 1) Determining the effects of the treatment PSG1 on central nervous...

Federal Project Grant Award Summary Astrocyte Pharmaceuticals Inc. received a $1.5M Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded on June 12, 2025, with completion by May 31, 2027. The project deliverable is the preclinical efficacy and safety evaluation of an oral tablet formulation of AST-004, a proprietary small molecule...

The University of Pittsburgh was awarded a $569,851 Project Grant by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to study the effectiveness of a traumatic brain injury whole blood test in improving assessment and triage for patients with mild traumatic brain injury presenting to civilian emergency departments. The award period runs from July 1, 2025 to June 30, 2029. The project aims to develop advanced diagnostic tools and clinical...

This federal Project Grant, awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research aimed at improving the assessment and triage of patients with mild traumatic brain injury presenting to civilian emergency departments. The $2,699,157 grant was awarded on July 1, 2025 to the University of Pittsburgh to evaluate the effectiveness of a traumatic brain injury whole blood test in this clinical setting. The research aims to...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $423,500 to The University of Kentucky Research Foundation to examine the role of transforming growth factor-activated kinase 1 (TAK1) in tau pathology following repetitive mild traumatic brain injury (TBI). The research aims to determine an optimal dosage and treatment regimen for the novel small molecule therapeutic BNC-1 to reduce TAK1 phosphorylation and tau pathology, neurodegeneration, and...

The Defense Health Agency awarded a $7,999,917 project grant under the Military Medical Research and Development (CFDA 12.420) program to The Research Foundation For The State University Of New York on behalf of Suny Downstate Health Sciences University. The four-year award beginning September 30, 2022 supports the "GAP-BASED MILIEU BIOMARKERS FOR TRAUMATIC BRAIN INJURY (GAMBIT-TBI)" program. Under the award, Suny Downstate and six sub-awardees - The Morehouse School Of Medicine, Inc.,...

This $309,279 Project Grant award, funded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports a research study on traumatic brain injury (TBI) and psychological health conducted by Florida State University. The primary objectives are to adapt the Ohio State University TBI Identification Method and the STAIR-NT intervention for first responders with TBI, analyze the data, and disseminate the study findings. Key sub-award activities...