Project Grant R21EB034428

Award Date 8/5/24
Completion Date 7/31/26
Dollars Obligated $390K
Federal Grant Program
93.286
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90095, USA

The National Institute of Biomedical Imaging and Bioengineering, under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, awarded a $389,813 Project Grant to the University of California, Los Angeles (UCLA) to develop and assess novel frameworks for accurately predicting functional recovery in patients with moderate-to-severe traumatic brain injury (TBI). Through this two-year project, UCLA's researchers aim to leverage non-parametric models and machine learning techniques to fuse and incorporate routine multimodal and multiplex magnetic resonance imaging (MRI) signals into a prediction framework. The goal is to create a tool that can be deployed in intensive care units to help guide medical decision-making in an evidence-based manner, potentially improving upon current clinical prognostication methods that tend to over-estimate poor outcomes and under-estimate positive outcomes. If successful, the intent is to further develop this research into a broadly accessible platform for practicing clinicians to supplement TBI prognosis with quantitative and spatial multimodal MRI data.

Generated 2/25/25, 5:36 AM