Project Grant SB1DE034606
- The Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), provides $306,633 to Ther-Ai LLC to develop CRANIAMAP, a foundational software module that enhances auto-segmentation and landmarking capabilities for cone beam computed tomography (CBCT) scans. This SBIR Phase I project aims to outperform existing AI-based tools, achieving at least 90% accuracy in segmenting critical...
- This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $113,727 to develop new geometric deep learning methods for the automated, real-time evaluation of head shapes using 3D photogrammetry. The goal is to create quantitative models to assess the normalization of head shape after corrective surgery for craniosynostosis, a condition characterized by the premature...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $350,000 project grant to Deep Reasoning AI Inc. The grant will support the development of the Deep Reasoning AI Virtual Anatomical Technology & Augmented Reasoning (DR-AIVATAR) platform, a multi-agent AI system for high-precision, personalized 3D anatomical modeling, surgical planning, and decision-making. The initial focus will be...
- This federal Project Grant award, valued at $294,000 and spanning September 2024 to September 2026, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The grant supports research to understand the mechanisms of craniofacial cartilage differentiation from human neural crest stem cells, with the goal of developing tissue engineering approaches to repair birth defects and injuries to the head and...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded Rytek Medical Inc. a $220,000 Project Grant on August 1, 2025. The grant supports research to evaluate CT/X-ray imaging-correlated impedance-based metrics for predicting surgical osseointegration and injury prevention in dental implant procedures. The project aims to develop innovative diagnostic technologies, such as an impedance-based...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,952,000 Project Grant under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) to Matregenix Inc., a small disadvantaged business located in California. The grant supports the development of MATRINOVA, an animal-free, amino acid-based biodegradable barrier membrane for guided bone regeneration in dental and craniomaxillofacial surgeries. The research aims to create a membrane with a unique...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $302,318 Project Grant under the Oral Diseases and Disorders Research Program (CFDA 93.121) to Rutgers, The State University. The grant will fund research to investigate the effects of skull malformations and intracranial hypertension on the glymphatic and meningeal lymphatic systems in craniosynostosis. Key aims include testing if impaired glymphatic (cerebrospinal fluid) influx and efflux impedes the clearance of...
- This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research to establish a novel zebrafish model of syndromic craniosynostosis. The $313,000 award to Emory University will enable comprehensive phenotypic, mechanistic, and genetic analyses of the craniosynostosis mutant zebrafish to better understand the underlying pathological mechanisms. The research aims to identify...
- The $296,171 Project Grant awarded on August 8, 2025 by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to design and evaluate an impedance-based bone assessment technology for characterizing trabecular bone microarchitecture. This technology is intended to address the limitations of current imaging techniques, like cone beam CT, in accurately quantifying bone quality, particularly in the trabecular...
- This Project Grant award, totaling $493,458, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program. The grant aims to investigate the role of ARID1 proteins in regulating cranial neural crest cell (CNCC) development, which is critical for proper craniofacial formation. The project will examine how ARID1A and ARID1B, subunits of the chromatin remodeling complex BAF, dynamically...
The National Institute of Dental and Craniofacial Research (NIDCR) has awarded a $1,000,000 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program to Pediametrix Inc., a woman-owned small business located in Rockville, Maryland. This 2-year project (August 2025 to August 2027) aims to commercialize the "SoftSpot TotalCare" mobile digital platform, which enables quantitative head shape assessment and early detection of infant cranial malformations such as craniosynostosis and deformational plagiocephaly. The platform allows pediatric providers and parents to capture 2D and 3D data of infant heads using smartphones or tablets, leveraging machine learning algorithms to analyze the data and facilitate early diagnosis and treatment. This project builds on previous NIDCR-funded research and development efforts by Pediametrix, with the goal of bringing this innovative pediatric health monitoring technology to the commercial market.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 8/12/25 |